7 results found for proteins

The selective degradation of many short-lived proteins in eukaryotic cells is carried out by the ubiquitin-mediated proteolytic system. In this pathway, proteins are targeted for degradation by covalent ligation to ubiquitin, a highly conserved small....

This lecture starts out with a very brief review of the history of protein crystallography and continue with our studies since 1970 on proteolytic enzymes and their control. Proteolytic enzymes catalyse a very simple chemical reaction, the hydrolytic....

This talk concentrates on cellular regulation by tyrosine phosphorylation which has been directly implicated in cell growth, differentiation and transformation. Growth factor receptors transduce their signal by recruiting a multiplicity of adaptor p....

It was in 1882 that Walther Flemming published drawings of chromosomes lining up in mitosis and parting equally to the daughters of cell division, and 20 years later that Theodor Boveri explained the significance of the chromosome dance in terms of t....

Argonaute proteins interact with small RNAs to mediate gene silencing. C. elegans contains 27 Argonaute homologs, raising the question of what roles these genes play in RNAi and related gene-silencing pathways. Through our collaborator, Dr. Shohei....

Young scientists like Maartje Bastings are set to revolutionise the way we deliver drugs. Her work will aid the development of 'smart drugs' which target specific proteins in the membranes of particular cells, proteins like the aquaporins discovered ....

The 2008 Nobel Prize in chemistry was awarded to Roger Tsien and colleagues for work on the green fluorescent protein (GFP). This protein, originally found in jellyfish, enables scientists to track the activity of individual proteins within living ce....