202 results found for lindau-nobel

G protein coupled receptors (GPCRs) conduct the majority of cellular responses to hormones and neurotransmitters, and are therefore the largest group of pharmaceutical targets for a broad spectrum of diseases.  Identification of genes for GPCRs, ini....

Olefin metathesis is an irresistible way to make C=C bonds catalytically in organic molecules and polymers, both as a consequence of its very nature, i.e. the synthesis of C=C bonds from C=C bonds, and because of the control that can be exercised thr....

Ribosomes, the universal cellular machines that translate the genetic code into proteins, are targeted by many antibiotics that paralyze them by binding to their functional sites.  Antibiotics binding modes, inhibitory actions and synergism pathways....

The oxygen, you breathe in, is converted to water by cytochrome c oxidase, using electrons provided by cytochrome c and protons from the aqueous milieu of the body.  This fundamental enzyme has been discovered already in 1886, and studied extensivel....

Many important drugs such as penicillin, aspirin, or digitalis, were discovered by serendipity - some by curious researchers who accidentally noted a "strange" phenomenon, and some by isolation of active ingredients form plants known for centuries to....

Much of the chemical industry is based on processes that were developed decades ago.  The change in the cost of petroleum carbon and energy sources and the need to control emissions of carbon dioxide and other pollutants will change the rules of the....

Supramolecular chemistry lies beyond molecular chemistry.  It aims at implementing highly complex chemical systems from molecular components held together by non-covalent intermolecular forces and effecting molecular recognition, catalysis and trans....

We consider two fields of single molecule studies of intermittently fluorescing systems.  In both fields the intermittency is assumed to involve diffusion controlled electron transfer.  One of these studies involves the initial steps in dye-sensiti....

As an introduction, some principles of nuclear spin physics applying to studies of integral membrane proteins (IMP) will be reviewed.  Applications of resulting nuclear magnetic resonance (NMR) techniques will then be illustrated with studies of G-p....

Research, at least my research, has never been linear.  I have found that my lab and I often double back on problems after years of inactivity or go off in entirely new directions as dictated by the work and people's interests.  This lack of direct....

Crystallography has been one of the mature sciences.  Over the years, the modern science of crystallography that started by experimenting with x-ray diffraction from crystals in 1912, has developed a major paradigm that all crystals are ordered and ....

Climate change represents one of the most serious challenges that society is facing in this century.  It is important for humanity to limit its interference with the climate system by profoundly modifying activities such as burning fossil fuels and ....