
Role of Cortical Noise in Vision
Our brains are always generating electrical signals, even if we close our eyes, plug our ears, and lie in a warm bath. These signals are called cortical noise because they don't correlate with any sensation or thought of which we are aware. I will ....
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The Individuality of Light Quanta
Light quanta are the fundamental units of radiant energy. When propagating freely they travel at the fastest attainable speed and live forever. These properties recommend them as the ideal messengers for communication of all sorts. Ordinary light ....
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Which Way For Physics?
This talk describes a new approach to the problem of characterising physical reality, one with the potential to fill in gaps in the conventional understanding of nature. It is based on a different view from the usual one of structure at the finest l....
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How Advances in Science are Made
How advances in science are made, and how they may come to benefit mankind at large are complex issues. The discoveries that most influence the way we think about nature seldom can be anticipated, and frequently the applications for new technologies....
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The Impact of Big Science on Astrophysics
The Chandra and Hubble Telescopes are in space and each costs (through operations) several billion dollars. VLT is on the ground but over 20 years of operations will also cost in excess of a billion. They all fall therefore in the category of what ....
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The Large Hadron Collider and the Super World
In the period 1990 to 2001 many powerful new astronomical observational facilities have become operational. Hubble Space telescope was launched in 1990; it was followed by the construction of Keck I in 1992 and Keck II in 1996, by the completion of....
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The Beginning and Development of the Universe
By careful investigation of relic left on the cosmic scene we have very good evidence and constraints on what has occurred since the beginning of the Universe. This talk reviews the evidence including images and information from the very first light....
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What Future for Energy and Climate?
We are using the planet's fossil fuel resources in a time which is very short compared to that of human evolution. In the same process we are changing the planet's climate and sea level, threatening the future of large segments of the global populat....
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The Development of Particle Physics
Particle physics mainly developed after World War II. It has its roots in the first half of the previous century, when it became clear that all matter is made up from atoms, and the atoms in turn were found to contain a nucleus surrounded by electro....
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Discovery of Superconducting Tunneling
I had the great fortune to receive a Nobel Prize in Physics for using electron tunneling to measure the energy gap in superconductors. In this talk I will recollect some of the events that led to this discovery and hopefully I will be able to convey....
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The Optical Frequency Comb – a Really Versatile Tool
The Optical Frequency Comb concept and technology exploded in 1999-2000 from the synthesis of advances in independent fields of Laser Stabilization, UltraFast Lasers, and NonLinear Optical Fibers. The Comb was developed first as a method for optical....
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Towards a Quantum Laboratory on a Chip
Microfabricated magnetic traps, waveguides, and other elements for the manipulation of ultracold atoms can be combined to form a quantum laboratory on a chip. Devices such as miniaturized atom lasers, atom interferometers, and atomic clocks have been....
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Cold Atomic Gases: the Intersection of Condensed Matter and Atomic Physics
During the past decade laser cooling and evaporative cooling of atoms have produced quantum degenerate gases both of bosons (Bose-Einstein condensates) and of fermions (gases with temperatures below the Fermi temperature). Such gases can provide ana....
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From Spinwaves to Giant Magnetoresistance (GMR) and Beyond
Standing spinwaves and surface waves in layered magnetic structures can be used for the detection and quantitative evaluation of interlayer exchange coupling (IEC). Using this method antiferromagnetic IEC has been found in Fe/Cr/Fe layered structure....
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Where Do Ideas Come From?
At many times in your scientific lives, you will hopefully have ideas - good or not so good- that will determine what you will do next. Where do ideas come from? My intention is to tell you where some of mine came from, and particularly those when I....
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Generating the Fuel of Life
The lecture will be devoted to the topic of how the biological world supplies itself with energy to make biology work, and what medical consequences ensue when the energy supply chain in our bodies is damaged or defective. We derive our energy from ....
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Tickling Worms: Surprises From Basic Research
Research, at least my research, has never been linear. I have found that my lab and I often double back on problems after years of inactivity or go off in entirely new directions as dictated by the work and peoples interests. This lack of direction....
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Biological Evolution in the Context of Cosmic Evolution and of Cultural Evolution
After reconsidering the very long time periods in cosmic evolution, we will focus our attention to the evolutionary development of living organisms on our planet Earth. The genetic variants (mutations), which are occasionally produced, are alteratio....
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Discovery of Nitric Oxide and Cyclic GMP in Cell Signaling and Their Role in Drug Development
The role of nitric oxide in cellular signaling in the past three decades has become one of the most rapidly growing areas in biology. Nitric oxide is a gas and a free radical with an unshared electron that can regulate an ever-growing list of biolog....
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Structural Biology and its Translation into Practice and Business: My Experience
As a student in the early 1960s, I had the privilege to attend winter seminars organized by my mentor, W. Hoppe, and by M. Perutz, which took place in a small guesthouse in the Bavarian-Austrian Alps. The entire community of a handful of protein cry....
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Structural Studies on Cholesterol Transport
Cholesterol has two essential functions in our bodies: It is an important component of cell membranes and it serves as the starting material for the synthesis of bile acids, steroid hormones, and other compounds. The human body obtains necessary cho....
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Membrane Proteins: Importance, Functions, Mechanisms
Biological membranes define and compartmentalize the cells of higher organisms. Consisting of membrane proteins and lipids, they are basically impermeable for ions and polar substances, so that electric voltages (_membrane potentialsî) and substanc....
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Short-term Synaptic Plasticity
Our brain is a network of about 10^11 neurons, which are connected via synapses. A neuron typically receives input from about 10000 other neurons, which can be either excitatory or inhibitory. The neuron integrates these inputs and generates an actio....
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Towards Adaptive Chemistry
Supramolecular chemistry lies beyond molecular chemistry. It aims at implementing highly complex chemical systems from molecular components held together by non-covalent intermolecular forces and effecting molecular recognition, catalysis and transp....
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