
The Optical Frequency Comb – a Really Versatile Tool
The Optical Frequency Comb concept and technology exploded in 1999-2000 from the synthesis of advances in independent fields of Laser Stabilization, UltraFast Lasers, and NonLinear Optical Fibers. The Comb was developed first as a method for optical....
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Towards a Quantum Laboratory on a Chip
Microfabricated magnetic traps, waveguides, and other elements for the manipulation of ultracold atoms can be combined to form a quantum laboratory on a chip. Devices such as miniaturized atom lasers, atom interferometers, and atomic clocks have been....
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Cold Atomic Gases: the Intersection of Condensed Matter and Atomic Physics
During the past decade laser cooling and evaporative cooling of atoms have produced quantum degenerate gases both of bosons (Bose-Einstein condensates) and of fermions (gases with temperatures below the Fermi temperature). Such gases can provide ana....
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From Spinwaves to Giant Magnetoresistance (GMR) and Beyond
Standing spinwaves and surface waves in layered magnetic structures can be used for the detection and quantitative evaluation of interlayer exchange coupling (IEC). Using this method antiferromagnetic IEC has been found in Fe/Cr/Fe layered structure....
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Where Do Ideas Come From?
At many times in your scientific lives, you will hopefully have ideas - good or not so good- that will determine what you will do next. Where do ideas come from? My intention is to tell you where some of mine came from, and particularly those when I....
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Generating the Fuel of Life
The lecture will be devoted to the topic of how the biological world supplies itself with energy to make biology work, and what medical consequences ensue when the energy supply chain in our bodies is damaged or defective. We derive our energy from ....
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Tickling Worms: Surprises From Basic Research
Research, at least my research, has never been linear. I have found that my lab and I often double back on problems after years of inactivity or go off in entirely new directions as dictated by the work and peoples interests. This lack of direction....
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Biological Evolution in the Context of Cosmic Evolution and of Cultural Evolution
After reconsidering the very long time periods in cosmic evolution, we will focus our attention to the evolutionary development of living organisms on our planet Earth. The genetic variants (mutations), which are occasionally produced, are alteratio....
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Discovery of Nitric Oxide and Cyclic GMP in Cell Signaling and Their Role in Drug Development
The role of nitric oxide in cellular signaling in the past three decades has become one of the most rapidly growing areas in biology. Nitric oxide is a gas and a free radical with an unshared electron that can regulate an ever-growing list of biolog....
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Structural Biology and its Translation into Practice and Business: My Experience
As a student in the early 1960s, I had the privilege to attend winter seminars organized by my mentor, W. Hoppe, and by M. Perutz, which took place in a small guesthouse in the Bavarian-Austrian Alps. The entire community of a handful of protein cry....
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Structural Studies on Cholesterol Transport
Cholesterol has two essential functions in our bodies: It is an important component of cell membranes and it serves as the starting material for the synthesis of bile acids, steroid hormones, and other compounds. The human body obtains necessary cho....
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Membrane Proteins: Importance, Functions, Mechanisms
Biological membranes define and compartmentalize the cells of higher organisms. Consisting of membrane proteins and lipids, they are basically impermeable for ions and polar substances, so that electric voltages (_membrane potentialsî) and substanc....
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