
The Killer Defence
Immune surveillance by virus-specific CD8+ cytotoxic T lymphocytes (CTLs), or killer T cells, has long been known to be central to the control of acute infections and some cancers, though the role of CTL memory in the rapid recall of immune protectio....
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Role of Nitric Oxide and Cyclic GMP in Cell Signaling and Drug Development
Nitric oxide research has grown rapidly with about 150,000 research publications describing its biological effects. It is an important messenger molecule that affects most tissues and biological processes. Many effects of nitric oxide are mediated by....
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Ion Channels: Their Discovery, their Function and their Role in Diseases
The concept of bioelectricity emerged in the late 18th century, based on the experiments of Galvani and Volta. Sixty years ago, Hodgkin and Huxley showed that the nerve impulse is a result of permeability changes of the nerve membrane. This raised th....
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The Origin of Reversible Protein Phosphorylation as a Regulatory Mechanism
Reversible protein phosphorylation can be considered one of the most prevalent mechanism by which eukaryotic cellular events are regulated. It is directly involved in numerous pathological conditions, and bacterial and viral diseases. This process wa....
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The Science of Chillies

Nanomaterials as growth effectors and imaging agents in rice plants and its scope in plant science
Ramya talks about the ways in which nanomaterials can affect rice-plant growth and also be used for imaging purposes. This talk was part of her PhD thesis defence.
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Prospects of extremophiles and sulfated polysaccharides in bionanotechnology and biomedicine
During his PhD thesis defence lecture, Sreejith looks at some novel prospects for biomedicine.
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Investigating the ribosome inactivating protein-curcin, as a protent therapeutic candidate in nano-drug delivery systems
During the defence of his doctoral thesis, Mohamed describes his work and investigation of curcin, the ribosome-inactivating protein and the ways it may be used in the treatment of cancer.
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Synthesis and characterization of targeted nano-regulators as potential therapeutic agents for controlling Alzheimer’s disease
In her PhD dissertation lecture, Anila describes the use of nano-particles in the treatment of Alzheimer's Disease.
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From bench to bedside: KATP channels and neonatal diabetes
Whether you eat a whole box of chocolates or fast for the day, the pancreatic beta-cells ensure that your blood glucose level remains relatively constant by regulating the release of insulin from the pancreatic beta-cells. Diabetes results when insul....
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Molecular chaperones: how cells stop proteins from misbehaving
Proteins are the action molecules of all cells, and to function properly, protein chains must fold and assemble correctly. But each chain of every protein runs the risk that it will combine with one or more identical chains to form nonfunctional aggr....
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Retinoblastoma
Kyla discusses an overview of the disease, the most common method in which it is diagnosed, as well as the major chemotherapeutics used to treat it.
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Bioenergetics of Cancer Cells
A brief summary from the literature about cancer cells' metabolism; 1) the major pathways cancer cells use to generate energy and macromolecules efficiently and rapidly and 2) the enzymes cancer cells up-regulate to control those pathways.
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Lapatinib treatment for HER2 Positive Breast Cancer
Discussion on the background information, etiology, and treatment of HER2 positive breast cancer.
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The Science of Love
A brief look into the physical, biological, chemical and behavioral attributes that humanity shares with other members of the animal kingdom focusing on studies done on Jamaican dancers, Belding's ground squirrels, human MHC and others.
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The great ideas of biology
Three of the ideas of biology are the gene theory, the theory of evolution by natural selection and the proposal that the cell is the fundamental unit of all life. A fourth idea is that the organization of chemistry within the cell provides explanati....
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The breakdown of macro-nutrients
Presentation on the breakdown of macro-nutrients. The chemical decomposition of macronutrients, which includes carbohydrates, proteins, and lipids.
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The new biology of ageing
Research into ageing has been rejuvenated by the discovery of mutations in single genes that extend the lifespan of laboratory animals. Some of the signalling pathways involved, particularly the insulin/Igf-like pathway, have effects on lifespan acro....
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A molecular window into speech and language
Our capacity for complex speech and language remains one of the most intriguing aspects of being human. It has long been suspected that some answers to this enigma will be found buried within the genome. With recent advances in genetic technologies, ....
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Plant and animal communication
Organisms of all kinds use signals comprising minute amounts of natural chemicals. The exploitation of semiochemicals is demonstrated with dramatic success in the management of pests and parasitic weeds in resource-poor East African cereal farming.
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From proteins to drugs
The normal proteins which circulate in human blood are either known or presumed to have beneficial functions. However normal immunity and inflammation proteins can cause or exacerbate disease in addition to helping to resist infections.
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Nuts and Bolts of the Mind
Susan Greenfield conducts us on an exhilarating tour of brain. A brief fascinating historical introduction is followed by a discussion on our present, admittedly limited, understanding of this amazing organ. Members of the group handle (and dissect) ....
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