Engineered zinc finger proteins and gene expression

View Engineered zinc finger proteins and gene expression

Presenter: Aaron Klug

Published: January 2010

Age: 18-22 and upwards

Views: 1248 views

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Type: Lectures

Source/institution: Royal Society


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It has long been the goal of molecular biologists to design DNA binding proteins for the specific control of gene expression. The zinc finger design, discovered by Sir Aaron Klug 20 years ago, is ideally suited for such purposes, discriminating between closely related sequences both in vitro and in vivo.

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