30 results found for structural

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00:29:00

How to Model the Action of Complex Biological Systems on a Molecular Level

by Arieh Warshel
How to Model the Action of Complex Biological Systems on a Molecular Level
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 2103 views
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Despite the enormous advances in structural studies of biological systems we are frequently left without a clear structure function correlation and cannot fully describe how different systems actually work. This introduces a major challenge for compu....

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00:26:00

NMR in Biology, Chemistry and Medicine

by Kurt Wurthrich
NMR in Biology, Chemistry and Medicine
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1649 views
Rating:

For the discovery of the physics phenomenon of nuclear magnetic resonance (NMR), Felix Bloch and Edward Purcell were awarded the Nobel Prize in Physics in 1952. NMR has then been used in a wide range of fundamental studies in physics, and in the 1960....

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00:31:00

Structural Aspects of Protease Control in Health and Disease

by Robert Huber
Structural Aspects of Protease Control in Health and Disease
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1297 views
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This lecture starts out with a very brief review of the history of protein crystallography and continue with our studies since 1970 on proteolytic enzymes and their control. Proteolytic enzymes catalyse a very simple chemical reaction, the hydrolytic....

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00:33:00

Programmed Cell Death in Development and Disease

by Robert Horvitz
Programmed Cell Death in Development and Disease
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1889 views
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Programmed cell death (often referred to as apoptosis) is a normal feature of animal development and tissue homeostasis. The misregulation of cell death has been implicated in a diversity of human disorders, including cancer, autoimmune diseases, he....

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00:32:00

Cultural Values of Scientific Knowledge

by Werner Arber
Cultural Values of Scientific Knowledge
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 2868 views
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The acquisition of scientific knowledge largely depends on the availability of appropriate research approaches and methodologies. Novel scientific knowledge represents cultural values. On the one hand, it enriches our world-view with impacts on our....

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00:30:00

From the Structure of the Ribosome to the Design of New Antibiotics

by Thomas Steitz
From the Structure of the Ribosome to the Design of New Antibiotics
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1756 views
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Structural studies of the ribosome exemplify the evolution of structural studies in cell biology from the early negatively stained images of macromolecular assemblies in whole cells, to a detailed atomic understanding of the mechanism of action of a ....

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00:41:00

Climbing the Everest Beyond the Everest

by Ada Yonath
Climbing the Everest Beyond the Everest
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1724 views
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The challenges associated with pursuing ribosomal crystallography can be described as a series of Everest climbing. At each step, when reaching the summit, a taller and more difficult one became exposed. Snapshots of this story will be described.__....

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00:33:00

Structural Biology and its Translation into Practice and Business: My Experience

by Robert Huber
Structural Biology and its Translation into Practice and Business: My Experience
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1588 views
Rating:

As a student in the early 1960s, I had the privilege to attend winter seminars organized by my mentor, W. Hoppe, and by M. Perutz, which took place in a small guesthouse in the Bavarian-Austrian Alps. The entire community of a handful of protein cry....

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00:34:00

Structural Studies on Cholesterol Transport

by Johann Deisenhofer
Structural Studies on Cholesterol Transport
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 2157 views
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Cholesterol has two essential functions in our bodies: It is an important component of cell membranes and it serves as the starting material for the synthesis of bile acids, steroid hormones, and other compounds. The human body obtains necessary cho....

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00:34:00

Towards Adaptive Chemistry

by Jean-Marie Lehn
Towards Adaptive Chemistry
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1361 views
Rating:

Supramolecular chemistry lies beyond molecular chemistry. It aims at implementing highly complex chemical systems from molecular components held together by non-covalent intermolecular forces and effecting molecular recognition, catalysis and transp....

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00:36:00

A Personal View of the History of Nuclear Magnetic Resonance in Biology and Medicine

by Kurt Wurthrich
A Personal View of the History of Nuclear Magnetic Resonance in Biology and Medicine
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1755 views
Rating:

In 1952, Felix Bloch and Edward Purcell were awarded the Nobel Prize in Physics for the description of the phenomenon of nuclear magnetic resonance (NMR). Over the years, NMR has been used in a wide range of fundamental studies in physics, and in the....

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00:28:00

From the Structure of the Ribosome to New Antibiotics

by Thomas Steitz
From the Structure of the Ribosome to New Antibiotics
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1490 views
Rating:

Structural studies of the ribosome exemplify the evolution of structural studies in cell biology from the early negatively stained images of macromolecular assemblies in whole cells, to a detailed atomic understanding of the mechanisms of action of a....

More details | Watch now

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