Engineered zinc finger proteins and gene expression
It has long been the goal of molecular biologists to design DNA binding proteins for the specific control of gene expression. The zinc finger design, discovered by Sir Aaron Klug 20 years ago, is ideally suited for such purposes, discriminating betwe....
More details | Watch nowDeciphering disease: cells and disruption of their communication
The human body may seem to be no more than a bundle of tissues and organs, yet the cells these are made from are capable of interacting, communicating and performing complex tasks. Our cells' capacity to interact in this way enables humans to adapt t....
More details | Watch nowStem Cells to Synapses
One of the goals of research in neurobiology is the repair and regeneration of neurons after damage to the brain or spinal cord. Before we can understand how to repair the nervous system we must first learn how the nervous system is put together.
More details | Watch nowStructure and the living cell
In this lecture Iain Campbell will discuss methods of studying the structure of molecules and cells and how they have advanced in the 350 years since early microscopes gave the first glimpse of single cells. He will show how modern methods are allowi....
More details | Watch nowMicroscopy goes cold: secrets of frozen viruses
Viruses are a major cause of death and disease. Too small to be seen by light microscopy, they were first visualised about 50 years ago by electron microscopy. Dr. Crowther describes his work on the development of the methods and illustrates how he h....
More details | Watch nowThe Puppet Master: How the brain controls the body
The effortless ease with which humans move our arms, our eyes, even our lips when we speak masks the true complexity of the control processes involved. Professor Daniel Wolpert explains how the brain deals with this and can perform optimally in the p....
More details | Watch nowBeyond the human genome project
Dr Lander and his colleagues have developed many of the key tools and generated many of the key information resources for modern mammalian genomics. Their work includes mapping and sequencing of the human, mouse, and other genomes. He was elected a m....
More details | Watch nowAdventures in vascular biology
Thirty years ago it was thought that the endothelium, a layer of thin, flat cells that line the interior surface of blood vessels was inert. However, major discoveries since then have demonstrated that it is a highly metabolic organ involved in maint....
More details | Watch nowGenes, worms and the new genetics
A surprising finding over the past 20 years is that all animals have many of the same genes and that they use them in similar ways to grow and develop. These similarities mean that much of what is learned about what genes do in simple animals such as....
More details | Watch nowMagnetic brain stimulation and brain function?
Like his nineteenth century contemporaries David Ferrier tried to reveal cerebral localisation of function by direct electrical stimulation of the exposed brain of animals. With some notable exceptions the results were disappointing and confined to t....
More details | Watch nowPerception, deception and reality
Sir David Attenborough delivers the 2003 Michael Faraday Lecture entitled: Perception, deception and reality
More details | Watch nowVision for knowledge: Knowledge for vision
An evolutionary development of perception is suggested - from passive reception to active perception to explicit conception - earlier stages being largely retained and incorporated in later species. A key is innate and then individually learned knowl....
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