135 results found for biology

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00:03:00

The Krebs Cycle

by Matt Johnson
The Krebs Cycle
for 11-14 and upwards,
Lectures | 11-14 and upwards | 7 years ago | 0 views
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Matt Johnson explains the Krebs Cycle, its discovery by a University of Sheffield Nobel Prize winner and its role in endurance sports such as cycling.

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00:35:00

Telomeres: Telling Tails

by Elizabeth Blackburn
Telomeres: Telling Tails
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1850 views
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Telomeres protect chromosome ends and help stabilize the genome. Throughout human life and in aging, telomeres often erode down, eventually causing cells to malfunction or die. The highly regulated cellular enzyme telomerase adds telomeric DNA to tel....

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00:29:00

The Killer Defence

by Peter Doherty
The Killer Defence
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1461 views
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Immune surveillance by virus-specific CD8+ cytotoxic T lymphocytes (CTLs), or killer T cells, has long been known to be central to the control of acute infections and some cancers, though the role of CTL memory in the rapid recall of immune protectio....

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00:31:00

Minimizing a Bacterial Genome by Global Design and Synthesis

by Hamilton Smith
Minimizing a Bacterial Genome by Global Design and Synthesis
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 2140 views
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In 2010, we chemically synthesized the 1078 Kb Mycoplasma mycoides genome and transplanted it into a recipient cell cytoplasm to create a 'synthetic cell', JCVI-syn1.0 (Science, 329, 52-56, 2010). We identified several hundred non-essential genes by ....

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00:39:00

Role of Nitric Oxide and Cyclic GMP in Cell Signaling and Drug Development

by Ferid Murad
Role of Nitric Oxide and Cyclic GMP in Cell Signaling and Drug Development
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1778 views
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Nitric oxide research has grown rapidly with about 150,000 research publications describing its biological effects. It is an important messenger molecule that affects most tissues and biological processes. Many effects of nitric oxide are mediated by....

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00:30:00

Ion Channels: Their Discovery, their Function and their Role in Diseases

by Erwin Neher
Ion Channels: Their Discovery, their Function and their Role in Diseases
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1560 views
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The concept of bioelectricity emerged in the late 18th century, based on the experiments of Galvani and Volta. Sixty years ago, Hodgkin and Huxley showed that the nerve impulse is a result of permeability changes of the nerve membrane. This raised th....

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00:31:00

The Origins of Cellular Life

by Jack Szostak
The Origins of Cellular Life
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1612 views
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The complexity of modern biological life has long made it difficult to understand how life could emerge spontaneously from the chemistry of the early earth. We are attempting to synthesize simple artificial cells in order to discover plausible pathwa....

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00:30:00

The Origin of Reversible Protein Phosphorylation as a Regulatory Mechanism

by Edmond Fischer
The Origin of Reversible Protein Phosphorylation as a Regulatory Mechanism
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1659 views
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Reversible protein phosphorylation can be considered one of the most prevalent mechanism by which eukaryotic cellular events are regulated. It is directly involved in numerous pathological conditions, and bacterial and viral diseases. This process wa....

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00:27:00

A Crime against Humanity

by Richard Roberts
A Crime against Humanity
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1707 views
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When Monsanto first tried to introduce GMO seeds into Europe there was a backlash by the Green parties and their political allies, who feared that American agro-business was about to take over their food supply. Thus began a massive campaign not agai....

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00:31:00

Finding Mutations that Affect Immunity

by Bruce Beutler
Finding Mutations that Affect Immunity
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1606 views
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Beginning with an exception to normal function caused by a genetic aberration, one may hope to find at least one protein with non-redundant function in a certain biological process. This approach permitted the identification of the receptor for bacte....

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00:34:00

Insight into the Laws of Nature for Biological Evolution

by Werner Arber
Insight into the Laws of Nature for Biological Evolution
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1708 views
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Both evolutionary biology and genetics have their roots 150 years ago in work with phenotypic variants of plants and animals. In contrast, microbial genetics originating as recently as the 1940s, rapidly revealed that filamentous DNA molecules are th....

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00:29:00

From Proto-oncogenes to Precision Oncology

by Harold Varmus
From Proto-oncogenes to Precision Oncology
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1815 views
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The diagnosis, classification, and treatment of human cancers are being transformed by scientific discoveries that were strongly influenced by the discovery of the c-src proto-oncogene, as described in the lecture by Michael Bishop. The path to this ....

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00:32:00

Tickling Worms – Surprises from Basic Research

by Martin Chalfie
Tickling Worms – Surprises from Basic Research
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1350 views
Rating:

Research, at least my research, has never been linear. I have found that my lab and I often double back on problems after years of inactivity or go off in entirely new directions as dictated by the work and people's interests This lack of direction r....

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00:29:00

How to Model the Action of Complex Biological Systems on a Molecular Level

by Arieh Warshel
How to Model the Action of Complex Biological Systems on a Molecular Level
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 2103 views
Rating:

Despite the enormous advances in structural studies of biological systems we are frequently left without a clear structure function correlation and cannot fully describe how different systems actually work. This introduces a major challenge for compu....

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00:25:00

Physical perspective on cytoplasmic streaming

by Ray Goldstein
Physical perspective on cytoplasmic streaming
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1282 views
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Professor Ray Goldstein FRS is the Schlumberger Professor of Complex Physical Systems at the University of Cambridge. Here he describes a biological example of topological inversion, with relevance to engineering problems in human technology.

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01:14:00

Cuckoos and their victims

by Nick Davies
Cuckoos and their victims
for 14-19 and upwards,
Lectures | 14-19 and upwards | 8 years ago | 1305 views
Rating:

The sight of a little warbler feeding an enormous cuckoo chick has astonished observers since ancient times. It was once thought that cuckoos were unable to raise their own young because of defective anatomy and behaviour, and so other birds were onl....

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01:10:00

Bacterial cell walls, antibiotics and the origins of life

by Jeff Errington
Bacterial cell walls, antibiotics and the origins of life
for 14-19 and upwards,
Lectures | 14-19 and upwards | 8 years ago | 1247 views
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The cell wall is a crucial structure found in almost all bacteria. It is the target for our best antibiotics and fragments of the wall trigger powerful innate immune responses against infection. Surprisingly, many bacteria can switch almost effortl....

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01:30:00

Horizons lecture series 4/23/15: BP’s Gulf Oil Spill

by Tallahassee Scientific Society
Horizons lecture series 4/23/15: BP’s Gulf Oil Spill
for All ages,
Lectures | All ages | 8 years ago | 1075 views
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01:09:00

Green Fluorescent Protein: Lighting up Life

by Martin Chalfie
Green Fluorescent Protein: Lighting up Life
for 14-19 and upwards,
Lectures | 14-19 and upwards | 9 years ago | 1470 views
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The accidental discovery of this wonderful tool has changed the face of biology.

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01:12:00

A Worm’s Tale: Secrets of Inheritance and Immortality

by Craig Mello
A Worm’s Tale: Secrets of Inheritance and Immortality
for 14-19 and upwards,
Lectures | 14-19 and upwards | 9 years ago | 1783 views
Rating:

Intracellular synthesis is immensely fast and complex.

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01:16:00

The End of Disease

by Roger Kornberg
The End of Disease
for 14-19 and upwards,
Lectures | 14-19 and upwards | 9 years ago | 1647 views
Rating:

The importance of transcription in cells and its effect on disease.

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00:57:00

Understanding the Cell cycle

by Paul Nurse
Understanding the Cell cycle
for 14-19 and upwards,
Lectures | 14-19 and upwards | 9 years ago | 1436 views
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How genes act to control the functioning of cells.

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00:09:00

The biology of Striga

by Various
The biology of Striga
for 14-19 and upwards,
Lectures | 14-19 and upwards | 9 years ago | 1840 views
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One of the major parasites is striga, a weed that sucks the juice and nutrients from cereal crops such as millet, sorghum and maize and causes great yield losses. A single striga plant can produce hundreds of thousands of seeds. The seeds are so tiny....

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00:12:00

‘Witch Weed’ – breaking the spell

by Various
‘Witch Weed’ – breaking the spell
for 14-19 and upwards,
Lectures | 14-19 and upwards | 9 years ago | 2780 views
Rating:

Striga (witchweed) is a parasitic weed that seriously constrains the productivity of staples such as maize, sorghum, millet and upland rice on some farms in Uganda.  Kilimo Trust supported this initiative to try and control its spread.

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