9 results found for biology

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00:35:00

Telomeres: Telling Tails

by Elizabeth Blackburn
Telomeres: Telling Tails
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1849 views
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Telomeres protect chromosome ends and help stabilize the genome. Throughout human life and in aging, telomeres often erode down, eventually causing cells to malfunction or die. The highly regulated cellular enzyme telomerase adds telomeric DNA to tel....

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00:31:00

Minimizing a Bacterial Genome by Global Design and Synthesis

by Hamilton Smith
Minimizing a Bacterial Genome by Global Design and Synthesis
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 2137 views
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In 2010, we chemically synthesized the 1078 Kb Mycoplasma mycoides genome and transplanted it into a recipient cell cytoplasm to create a 'synthetic cell', JCVI-syn1.0 (Science, 329, 52-56, 2010). We identified several hundred non-essential genes by ....

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00:31:00

The Origins of Cellular Life

by Jack Szostak
The Origins of Cellular Life
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1612 views
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The complexity of modern biological life has long made it difficult to understand how life could emerge spontaneously from the chemistry of the early earth. We are attempting to synthesize simple artificial cells in order to discover plausible pathwa....

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00:27:00

A Crime against Humanity

by Richard Roberts
A Crime against Humanity
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1707 views
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When Monsanto first tried to introduce GMO seeds into Europe there was a backlash by the Green parties and their political allies, who feared that American agro-business was about to take over their food supply. Thus began a massive campaign not agai....

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00:31:00

Finding Mutations that Affect Immunity

by Bruce Beutler
Finding Mutations that Affect Immunity
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1606 views
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Beginning with an exception to normal function caused by a genetic aberration, one may hope to find at least one protein with non-redundant function in a certain biological process. This approach permitted the identification of the receptor for bacte....

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00:34:00

Insight into the Laws of Nature for Biological Evolution

by Werner Arber
Insight into the Laws of Nature for Biological Evolution
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1708 views
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Both evolutionary biology and genetics have their roots 150 years ago in work with phenotypic variants of plants and animals. In contrast, microbial genetics originating as recently as the 1940s, rapidly revealed that filamentous DNA molecules are th....

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00:29:00

From Proto-oncogenes to Precision Oncology

by Harold Varmus
From Proto-oncogenes to Precision Oncology
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1814 views
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The diagnosis, classification, and treatment of human cancers are being transformed by scientific discoveries that were strongly influenced by the discovery of the c-src proto-oncogene, as described in the lecture by Michael Bishop. The path to this ....

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00:31:00

Biological Evolution in the Context of Cosmic Evolution and of Cultural Evolution

by Werner Arber
Biological Evolution in the Context of Cosmic Evolution and of Cultural Evolution
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1589 views
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After reconsidering the very long time periods in cosmic evolution, we will focus our attention to the evolutionary development of living organisms on our planet Earth. The genetic variants (mutations), which are occasionally produced, are alteratio....

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00:35:00

GFP and After

by Martin Chalfie
GFP and After
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1696 views
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Since its introduction as a biological marker, the Aequorea victoria Green Fluorescent Protein (GFP) has had a strong impact in biology, being used in an ever-increasing variety of ways. I will review a bit of the history of GFP and show how having ....

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