C60+ in space – a 28-year detective story about the Diffuse Interstellar Bands – Part 5
It seems likely that C60+ will act as a stable site for a wide variety of adducts and that these entities will contribute to the Diffuse Interstellar Bands. John Maier's group in Basel is looking for species like C60(Fe)+.
More details | Watch nowIdeas Come from Many Places
Come share with me the memories of where ideas have come from during my life - from childhood to old age. You may find it helpful in encouraging your own brains to come up with new ideas. They won't all be useful - as I have found in this case of min....
More details | Watch nowThe Discovery of Helicobacter
Before the 1970s, well fixed specimens of gastric mucosa were rare. Then the flexible endoscope was introduced. This enabled gastroenterologists to take numerous well-fixed small biopsies from the stomach. Gastric histology and pathology were clearly....
More details | Watch nowTelomeres: Telling Tails
Telomeres protect chromosome ends and help stabilize the genome. Throughout human life and in aging, telomeres often erode down, eventually causing cells to malfunction or die. The highly regulated cellular enzyme telomerase adds telomeric DNA to tel....
More details | Watch nowThe Killer Defence
Immune surveillance by virus-specific CD8+ cytotoxic T lymphocytes (CTLs), or killer T cells, has long been known to be central to the control of acute infections and some cancers, though the role of CTL memory in the rapid recall of immune protectio....
More details | Watch nowMinimizing a Bacterial Genome by Global Design and Synthesis
In 2010, we chemically synthesized the 1078 Kb Mycoplasma mycoides genome and transplanted it into a recipient cell cytoplasm to create a 'synthetic cell', JCVI-syn1.0 (Science, 329, 52-56, 2010). We identified several hundred non-essential genes by ....
More details | Watch nowRole of Nitric Oxide and Cyclic GMP in Cell Signaling and Drug Development
Nitric oxide research has grown rapidly with about 150,000 research publications describing its biological effects. It is an important messenger molecule that affects most tissues and biological processes. Many effects of nitric oxide are mediated by....
More details | Watch nowIon Channels: Their Discovery, their Function and their Role in Diseases
The concept of bioelectricity emerged in the late 18th century, based on the experiments of Galvani and Volta. Sixty years ago, Hodgkin and Huxley showed that the nerve impulse is a result of permeability changes of the nerve membrane. This raised th....
More details | Watch nowThe Origins of Cellular Life
The complexity of modern biological life has long made it difficult to understand how life could emerge spontaneously from the chemistry of the early earth. We are attempting to synthesize simple artificial cells in order to discover plausible pathwa....
More details | Watch nowThe Origin of Reversible Protein Phosphorylation as a Regulatory Mechanism
Reversible protein phosphorylation can be considered one of the most prevalent mechanism by which eukaryotic cellular events are regulated. It is directly involved in numerous pathological conditions, and bacterial and viral diseases. This process wa....
More details | Watch nowThe Adventure of Cold Atoms. From Optical Pumping to Quantum Gases
Conservation laws are very important in quantum physics. Two examples of applications will be given. First, optical pumping which uses transfer of angular momentum from polarized photons to atoms to produce highly polarized atomic gases. Then, laser ....
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