The Ubiquitin System
The selective degradation of many short-lived proteins in eukaryotic cells is carried out by the ubiquitin-mediated proteolytic system. In this pathway, proteins are targeted for degradation by covalent ligation to ubiquitin, a highly conserved sma....
More details | Watch nowAn Introduction to Prions
How embryos build organs to last a lifetime
All the organs of our body originate from small founder populations of cells which multiply into complex structures. ÊAdult stem cells are used to maintain organs throughout adult life and to repair or regenerate them after damage.Ê Focusing on the....
More details | Watch nowHelix – Episode 2 – Tay-Sachs Disease
In this episode of Helix, Patricia Martin outlines the symptoms and complications associated with the terminal illness Tay-Sachs disease.
More details | Watch nowSynthesis and characterization of targeted nano-regulators as potential therapeutic agents for controlling Alzheimer’s disease
In her PhD dissertation lecture, Anila describes the use of nano-particles in the treatment of Alzheimer's Disease.
More details | Watch nowThe Road to the Nobel Prize – Lessons from a life with the Helicobacter pylori
In 2005 Barry J. Marshall and J. Robin Warren were awarded the Nobel Prize for Physiology or Medicine in recognition of their 1982 discovery that a bacterium, Helicobacter pylori, causes one of the most common and important diseases of mankind, pepti....
More details | Watch nowWinning and losing the fight against infectious diseases
Human infectious diseases will be eliminated and replaced by chronic ÒlifestyleÓ diseases as fertility falls, life expectancy increases, and populations grow older and wealthier. This is the standard story of the epidemiologic transition, but it is....
More details | Watch nowThe art of stealth: a virus in my liver
The liver is a vital organ that works like a chemical factory every day to keep you alive. But what exactly does it do and how do viruses exploit it to hide from the immune system? With help from volunteers, Dr Zania Stamataki will demonstrate some....
More details | Watch nowStem cells: a cure for blindness?
Retinal degeneration is a leading cause of blindness in the western world. Drug treatments currently available only serve to slow the diseaseÕs progress and are not always successful. Rachael Pearson has helped develop a novel therapeutic approach t....
More details | Watch nowConfronting the Silent Tragedy of Skin Disease
How many people do skin conditions affect in the developing world? Approximately 3 billion people living in remote areas of 127 developing countries are deprived of even the most basic dermatological care which constitutes approximately one half of....
More details | Watch nowSoy – The Healthiest Food in the World?
The inhabitants of the Japanese region of Okinawa are officially the longest lived population in the world and also have one of the lowest mortality rates from chronic diseases like heart disease, cancer and dementia. This has in part been ascribed....
More details | Watch nowChemistry: A Key to Human Progress
Basic research in science has greatly increased our understanding of nature, expanded frontiers of inquiry, shown us how little we know, triggered creative waves of invention and innovation, and prompted technological breakthroughs that were inconcei....
More details | Watch now