88 results found for disease

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00:35:00

Telomeres: Telling Tails

by Elizabeth Blackburn
Telomeres: Telling Tails
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1849 views
Rating:

Telomeres protect chromosome ends and help stabilize the genome. Throughout human life and in aging, telomeres often erode down, eventually causing cells to malfunction or die. The highly regulated cellular enzyme telomerase adds telomeric DNA to tel....

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00:30:00

Ion Channels: Their Discovery, their Function and their Role in Diseases

by Erwin Neher
Ion Channels: Their Discovery, their Function and their Role in Diseases
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1559 views
Rating:

The concept of bioelectricity emerged in the late 18th century, based on the experiments of Galvani and Volta. Sixty years ago, Hodgkin and Huxley showed that the nerve impulse is a result of permeability changes of the nerve membrane. This raised th....

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00:30:00

The Origin of Reversible Protein Phosphorylation as a Regulatory Mechanism

by Edmond Fischer
The Origin of Reversible Protein Phosphorylation as a Regulatory Mechanism
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1658 views
Rating:

Reversible protein phosphorylation can be considered one of the most prevalent mechanism by which eukaryotic cellular events are regulated. It is directly involved in numerous pathological conditions, and bacterial and viral diseases. This process wa....

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00:31:00

Finding Mutations that Affect Immunity

by Bruce Beutler
Finding Mutations that Affect Immunity
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1606 views
Rating:

Beginning with an exception to normal function caused by a genetic aberration, one may hope to find at least one protein with non-redundant function in a certain biological process. This approach permitted the identification of the receptor for bacte....

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00:32:00

Tickling Worms – Surprises from Basic Research

by Martin Chalfie
Tickling Worms – Surprises from Basic Research
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1350 views
Rating:

Research, at least my research, has never been linear. I have found that my lab and I often double back on problems after years of inactivity or go off in entirely new directions as dictated by the work and people's interests This lack of direction r....

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00:33:00

Molecules Against Cancer or for Long-Term Memory Storage

by Roger Tsien
Molecules Against Cancer or for Long-Term Memory Storage
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1188 views
Rating:

For cancer diagnosis and therapy, we are developing activatable cell penetrating peptides (ACPPs), synthetic molecules with a novel amplifying mechanism for homing to diseased tissues. ACPPs are polycationic cell penetrating peptides whose cellular u....

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00:29:00

Are We Going to Cure all Diseases and at What Price?

by Aaron Ciechanover
Are We Going to Cure all Diseases and at What Price?
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1708 views
Rating:

We are exiting the era where our approach to treatment of these and many other diseases is 'one size fits all', and enter a new era of 'personalized medicine' where we shall tailor the treatment according to the patient's molecular/mutational profile....

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00:27:00

Roles of the Ubiquitin System in Health and Disease

by Avram Hershko
Roles of the Ubiquitin System in Health and Disease
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1299 views
Rating:

The selective degradation of many short-lived proteins in eukaryotic cells is carried out by the ubiquitin-mediated proteolytic system. In this pathway, proteins are targeted for degradation by covalent ligation to ubiquitin, a highly conserved small....

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00:31:00

Structural Aspects of Protease Control in Health and Disease

by Robert Huber
Structural Aspects of Protease Control in Health and Disease
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1297 views
Rating:

This lecture starts out with a very brief review of the history of protein crystallography and continue with our studies since 1970 on proteolytic enzymes and their control. Proteolytic enzymes catalyse a very simple chemical reaction, the hydrolytic....

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00:05:00

Helix – Episode 8 – Wilson Disease

by Patricia Martin
Helix – Episode 8 – Wilson Disease
for 11-14 and upwards,
Undergraduate presentations | 11-14 and upwards | 8 years ago | 1747 views
Rating:

This episode outlines details about Wilson disease, a rare disorder involving the amounts of copper in the body,  and the negative effects on vision and different organs.

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01:16:00

The End of Disease

by Roger Kornberg
The End of Disease
for 14-19 and upwards,
Lectures | 14-19 and upwards | 9 years ago | 1647 views
Rating:

The importance of transcription in cells and its effect on disease.

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00:03:00

2014 3MT Competition Finals: Early Disease Detection by Designing Better Sensors

by Rachel Armstrong
2014 3MT Competition Finals: Early Disease Detection by Designing Better Sensors
for 18-22 and upwards22 and upwards,
Postgraduate presentations | 18-22 and upwards22 and upwards | 9 years ago | 5486 views
Rating:

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00:05:00

Helix – Episode 6 – Sickle Cell Disease

by Patricia Martin
Helix – Episode 6 – Sickle Cell Disease
for 11-14 and upwards,
Undergraduate presentations | 11-14 and upwards | 9 years ago | 4584 views
Rating:

In this episode of Helix, Patricia Martin outlines the symptoms and causes of sickle cell disease (also referred to as sickle cell anemia), a hemoglobin-affecting disorder.

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01:00:00

Harnessing the power of mobile phones and big data for global health

by Rachel McKendry
Harnessing the power of mobile phones and big data for global health
for 14-19 and upwards,
Lectures | 14-19 and upwards | 9 years ago | 1319 views
Rating:

Infectious diseases rank among the gravest threats to human health alongside global warming and terrorism. New strains continue to evolve every year and can spread rapidly. The consequences can be devastating. The 1918 Spanish flu killed an estimated....

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00:31:00

HIV, a Discovery Highlighting the Global Benefit of Translational Research

by Francoise Barre-Sinoussi
HIV, a Discovery Highlighting the Global Benefit of Translational Research
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1498 views
Rating:

The fantastic progress made in medicine led the scientific community to hope about the complete eradication of infectious diseases in the middle of the 20th century. The sudden emergence of AIDS in the early 80's cruelly reminded us that this dream ....

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00:33:00

Programmed Cell Death in Development and Disease

by Robert Horvitz
Programmed Cell Death in Development and Disease
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1888 views
Rating:

Programmed cell death (often referred to as apoptosis) is a normal feature of animal development and tissue homeostasis. The misregulation of cell death has been implicated in a diversity of human disorders, including cancer, autoimmune diseases, he....

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00:28:00

DNA between Physics and Biology

by Luc Montagnier
DNA between Physics and Biology
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1928 views
Rating:

The association of DNA with water is known since the deciphering of its double helical structure by X-Ray diffraction in 1953 (Watson, Crick, Wilkins and Franklin). However the power of DNA for organizing water seems to go far beyond the direct fill....

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00:34:00

Discovery of Nitric Oxide and Cyclic GMP in Cell Signalling and their Role in Drug Development

by Ferid Murad
Discovery of Nitric Oxide and Cyclic GMP in Cell Signalling and their Role in Drug Development
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 2893 views
Rating:

The role of nitric oxide in cellular signaling in the past three decades has become one of the most rapidly growing areas in biology. Nitric oxide is a gas and a free radical with an unshared electron that can regulate an ever-growing list of biolog....

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00:41:00

Telomeres and Telomerase in Human Health and Disease

by Elizabeth Blackburn
Telomeres and Telomerase in Human Health and Disease
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 2848 views
Rating:

Telomeres are the protective tips that stabilize the ends of chromosomes. The function of telomeres is to allow cells to divide while holding the genetic material intact. Telomeres contain specialized, simple repetitive DNA sequences that, together....

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00:32:00

The Optical Frequency Comb – a Really Versatile Tool

by John Hall
The Optical Frequency Comb – a Really Versatile Tool
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1387 views
Rating:

The Optical Frequency Comb concept and technology exploded in 1999-2000 from the synthesis of advances in independent fields of Laser Stabilization, UltraFast Lasers, and NonLinear Optical Fibers. The Comb was developed first as a method for optical....

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00:37:00

Generating the Fuel of Life

by John Walker
Generating the Fuel of Life
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1372 views
Rating:

The lecture will be devoted to the topic of how the biological world supplies itself with energy to make biology work, and what medical consequences ensue when the energy supply chain in our bodies is damaged or defective. We derive our energy from ....

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00:32:00

Tickling Worms: Surprises From Basic Research

by Martin Chalfie
Tickling Worms: Surprises From Basic Research
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1268 views
Rating:

Research, at least my research, has never been linear. I have found that my lab and I often double back on problems after years of inactivity or go off in entirely new directions as dictated by the work and peoples interests. This lack of direction....

More details | Watch now
00:42:00

Discovery of Nitric Oxide and Cyclic GMP in Cell Signaling and Their Role in Drug Development

by Ferid Murad
Discovery of Nitric Oxide and Cyclic GMP in Cell Signaling and Their Role in Drug Development
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 2373 views
Rating:

The role of nitric oxide in cellular signaling in the past three decades has become one of the most rapidly growing areas in biology. Nitric oxide is a gas and a free radical with an unshared electron that can regulate an ever-growing list of biolog....

More details | Watch now
00:33:00

Structural Biology and its Translation into Practice and Business: My Experience

by Robert Huber
Structural Biology and its Translation into Practice and Business: My Experience
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1588 views
Rating:

As a student in the early 1960s, I had the privilege to attend winter seminars organized by my mentor, W. Hoppe, and by M. Perutz, which took place in a small guesthouse in the Bavarian-Austrian Alps. The entire community of a handful of protein cry....

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