Breast Cancer Susceptibility Gene BRCA2
BRAC2 is a tumor suppressor gene. Its protein product interacts with other proteins to assist regulation of DNA repair, transcription and cell cycle checkpoints. BRAC2 gene disruption may lead to protein truncation, mutations and loss of function. Ce....
More details | Watch nowRetinoblastoma
Kyla discusses an overview of the disease, the most common method in which it is diagnosed, as well as the major chemotherapeutics used to treat it.
More details | Watch nowHuman Papilloma Virus
The aim of this presentation is to provide an overview of the Human Papilloma Virus (HPV) and the associated carcinogenic pathologies of HPV. The predominant cellular players discussed in HPV pathologies are p53 and viral oncoprotein E6. In addition,....
More details | Watch nowBioenergetics of Cancer Cells
A brief summary from the literature about cancer cells' metabolism; 1) the major pathways cancer cells use to generate energy and macromolecules efficiently and rapidly and 2) the enzymes cancer cells up-regulate to control those pathways.
More details | Watch nowLapatinib treatment for HER2 Positive Breast Cancer
Discussion on the background information, etiology, and treatment of HER2 positive breast cancer.
More details | Watch nowMicrofluidic Biosensor
University of Toronto student Jonathan Yam describes his research on microfluidics during Summer 2010 in the laboratory of Bob Westervelt at Harvard University under the direction of Alex Nemiroski.
More details | Watch nowThe cuckoo egg mystery
Everything we touch is dirty!
Pandemic Influenza: one flu over the cuckoo’s nest
Where do the pandemic influenza viruses come from and why did experts fail to predict the severity of the 2009 pandemic? However to date, the 2009 H1N1 pandemic influenza has been much less severe than the 1918 Spanish influenza.
More details | Watch nowNetworks in ecosystems and financial systems
This talk surveys our growing understanding of the relationships between the network structure of ecological networks ? both in mathematical models and in the real world ? and their ability to withstand disturbance, natural or human-created.
More details | Watch nowCloning, stem cells and regenerative medicine
Extraordinary opportunities to study the molecular mechanisms that cause inherited diseases are being provided by new methods of producing stem cells. Hear about not only the potential value of these new methods, but also how their development was pr....
More details | Watch nowOur genomes, our history
Genetic differences between humans reflect the fundamental processes, such as mutation, recombination and natural selection, which have influenced our evolutionary history. Now that we can chart the genomes of many individuals, we are finding many su....
More details | Watch nowOrigin of Life on Earth: Abiogenesis
This presentation portrays a general overview of the theory of abiogenesis and its conceptual history. From the theory of spontaneous generation to biogenesis to the modern-day abiogenesis, the changing perception of the origin of life is discussed.....
More details | Watch nowCape Gannets
Study on Cape Gannets, a new prey for quickly adapting Great White Pelicans on Malgas Island, South Africa. First observed in 2008. Result of indirect human involvement; Cape Gannets should be reconsidered for conservation management.
More details | Watch nowBody Fuel for Long Distances
In my geoset project I will be discussing the effects of nutrition in long distance endurance. Topics include saturating carbohydrate stores before a race, the Krebs (citric acid) cycle, the effects of dehydration and hyponatremia, and replenishing y....
More details | Watch nowGenetic Programming
Genetic Programming is an artifical intelligence technique based off of natural selection. A generation of programs is generated, then tested using a fitness function. After that successful programs are altered and replicated successively until a d....
More details | Watch nowThe Science of Addiction
This presentation deals with common additives in cigarettes, including nicotine, and how these affect your body.
More details | Watch nowPharmaco-genomics
This is a brief presentation discussing the emerging field of pharmaco-genomics. It explains how understanding the human genome can lead to better drug therapy in the future including tailor-made drugs for individuals.
More details | Watch nowThe Science of Love
A brief look into the physical, biological, chemical and behavioral attributes that humanity shares with other members of the animal kingdom focusing on studies done on Jamaican dancers, Belding's ground squirrels, human MHC and others.
More details | Watch nowTissue Engineering
Mariah Michael discusses the burgeoning field of tissue engineering and the research being done at Wake Forest University under Dr. Anthony Atala. Each year, thousands of patients die while waiting for an organ transplant. With this technology, patie....
More details | Watch nowGenetically Modified Organisms
A brief overview of genetically modified organisms and their effect on the global population.
More details | Watch nowMammalian biodiversity: past, present, future?
Beautiful and charismatic, mammals are biodiversity icons. But a quarter of mammalian species are now threatened with extinction, as ecosystems reel under the impact of a growing and ever more demanding human population. This lecture explores the his....
More details | Watch nowThree score years and then? The new biology of ageing
Ageing is the single greatest challenge facing our society today. Recent breakthroughs have demonstrated that it is possible to combine a long life with the absence of age-related disease. Scientists at the forefront of this research will explain the....
More details | Watch nowGenetic fingerprinting and beyond
Professor Jeffreys will describe how DNA typing can be used to solve casework and will review the latest developments, including the creation of major national DNA databases that are proving extraordinarily effective in the fight against crime.
More details | Watch nowThe Music of Life
This event at Sheffield University formed part of a series on Arts-Science Encounters. Stories from The Music of Life related by Denis Noble are interwoven with performances of relevant pieces of classical guitar music by the world-class performer, C....
More details | Watch nowThe great ideas of biology
Three of the ideas of biology are the gene theory, the theory of evolution by natural selection and the proposal that the cell is the fundamental unit of all life. A fourth idea is that the organization of chemistry within the cell provides explanati....
More details | Watch nowPlasticity of the brain: the key to human development.
How do our genes program the complexity of our brains? Why is human culture so much richer than that of the Great Apes? And how has human cognitive achievement continued to accelerate, when our genetic makeup has changed very little over the past 100....
More details | Watch nowThe breakdown of macro-nutrients
Presentation on the breakdown of macro-nutrients. The chemical decomposition of macronutrients, which includes carbohydrates, proteins, and lipids.
More details | Watch nowMitochondrial DNA Testing
Neurochemistry
A presentation on neurochemistry - the effects of drugs and nutrition are also discussed.
More details | Watch nowThe Neuroscience of Music
Thinking like a vegetable: how plants decide what to do
Plants monitor a wide range of information from their surrounding environment. They combine information of multiple sorts, and respond in an appropriate way. In plants there is no brain, and the information processing is distributed across the plant ....
More details | Watch nowBrain development and brain repair.
The human brain is made up of close to a trillion nerve cells (or neurons), each of which makes connections with, on average, hundreds of other nerve cells, to form the complex neuronal circuits that control all brain activities, including perception....
More details | Watch nowEngineered zinc finger proteins and gene expression
It has long been the goal of molecular biologists to design DNA binding proteins for the specific control of gene expression. The zinc finger design, discovered by Sir Aaron Klug 20 years ago, is ideally suited for such purposes, discriminating betwe....
More details | Watch nowDeciphering disease: cells and disruption of their communication
The human body may seem to be no more than a bundle of tissues and organs, yet the cells these are made from are capable of interacting, communicating and performing complex tasks. Our cells' capacity to interact in this way enables humans to adapt t....
More details | Watch nowStem Cells to Synapses
One of the goals of research in neurobiology is the repair and regeneration of neurons after damage to the brain or spinal cord. Before we can understand how to repair the nervous system we must first learn how the nervous system is put together.
More details | Watch nowStructure and the living cell
In this lecture Iain Campbell will discuss methods of studying the structure of molecules and cells and how they have advanced in the 350 years since early microscopes gave the first glimpse of single cells. He will show how modern methods are allowi....
More details | Watch nowMicroscopy goes cold: secrets of frozen viruses
Viruses are a major cause of death and disease. Too small to be seen by light microscopy, they were first visualised about 50 years ago by electron microscopy. Dr. Crowther describes his work on the development of the methods and illustrates how he h....
More details | Watch nowThe Puppet Master: How the brain controls the body
The effortless ease with which humans move our arms, our eyes, even our lips when we speak masks the true complexity of the control processes involved. Professor Daniel Wolpert explains how the brain deals with this and can perform optimally in the p....
More details | Watch nowBeyond the human genome project
Dr Lander and his colleagues have developed many of the key tools and generated many of the key information resources for modern mammalian genomics. Their work includes mapping and sequencing of the human, mouse, and other genomes. He was elected a m....
More details | Watch nowAdventures in vascular biology
Thirty years ago it was thought that the endothelium, a layer of thin, flat cells that line the interior surface of blood vessels was inert. However, major discoveries since then have demonstrated that it is a highly metabolic organ involved in maint....
More details | Watch nowGenes, worms and the new genetics
A surprising finding over the past 20 years is that all animals have many of the same genes and that they use them in similar ways to grow and develop. These similarities mean that much of what is learned about what genes do in simple animals such as....
More details | Watch nowMagnetic brain stimulation and brain function?
Like his nineteenth century contemporaries David Ferrier tried to reveal cerebral localisation of function by direct electrical stimulation of the exposed brain of animals. With some notable exceptions the results were disappointing and confined to t....
More details | Watch nowPerception, deception and reality
Sir David Attenborough delivers the 2003 Michael Faraday Lecture entitled: Perception, deception and reality
More details | Watch nowVision for knowledge: Knowledge for vision
An evolutionary development of perception is suggested - from passive reception to active perception to explicit conception - earlier stages being largely retained and incorporated in later species. A key is innate and then individually learned knowl....
More details | Watch nowScience not stamp collecting? Botany from 1759 to 2059
Professor Hopper considers the vital role that the study of plant taxonomy and systematics has played in plant science. He considers, in particular, how these fields are transforming to meet the needs of 21st Century science as we address the challen....
More details | Watch nowThe origins of flowers
Flowers are such a ubiquitous and familiar part of our modern world that it is easy to take them for granted. But as Darwin recognized, the exquisite details of their structure and appearance have been shaped by evolutionary processes over millions o....
More details | Watch nowIs the Great Barrier Reef on Death Row?
Professor J.E.N Veron, the former Chief Scientist of the Australian Institute of Marine Science and widely regarded as the world's leading authority on coral reef ecosystems, presents the effects that climate change is having on coral reefs.
More details | Watch nowWe are what we remember.
n this lecture, Eric R Kandel considers the neural systems and molecular mechanisms that contribute to learning and long-term memory and discusses how our insights into memory storage are allowing us to understand various forms of age related memory ....
More details | Watch nowDeep sea discoveries
Recent underwater images show that the deep sea realm of the British Isles is nothing like the monotonous expanse of mud that many people imagine. Spectacular coral reefs, once thought to be restricted to the tropics, are now known to occur in the ch....
More details | Watch nowEvolution and Creationism
Dr Adam Rutherford investigates the idea that the teaching of evolution is being threatened by a rise in creationism amongst religious students.nRutherford speaks to the former Director of Education at the Royal Society, Reverend Professor Michael Re....
More details | Watch nowReprogramming the code of life
The information for synthesizing the molecules that allow organisms to survive and replicate is encoded in genomic DNA. In the cell, DNA is copied to messenger RNA, and triplet codons in the messenger RNA are decoded in the process of translation to ....
More details | Watch nowThe new biology of ageing
Research into ageing has been rejuvenated by the discovery of mutations in single genes that extend the lifespan of laboratory animals. Some of the signalling pathways involved, particularly the insulin/Igf-like pathway, have effects on lifespan acro....
More details | Watch nowA molecular window into speech and language
Our capacity for complex speech and language remains one of the most intriguing aspects of being human. It has long been suspected that some answers to this enigma will be found buried within the genome. With recent advances in genetic technologies, ....
More details | Watch nowMapping memory: the brains behind remembering
Historically memory research has focussed on the hippocampus, a structure deep in the brain's temporal lobes. Damage to the hippocampus is known to have a devastating impact on the ability to form new memories as well as compromising recollection of ....
More details | Watch nowPlant and animal communication
Organisms of all kinds use signals comprising minute amounts of natural chemicals. The exploitation of semiochemicals is demonstrated with dramatic success in the management of pests and parasitic weeds in resource-poor East African cereal farming.
More details | Watch nowFrom proteins to drugs
The normal proteins which circulate in human blood are either known or presumed to have beneficial functions. However normal immunity and inflammation proteins can cause or exacerbate disease in addition to helping to resist infections.
More details | Watch nowDecoding consciousness
Everything we know about the world comes to us through our brain. Yet for each of us our own conscious mental world of thoughts and feelings is isolated and private. Despite centuries of research, language or gesture remains the only way we can disco....
More details | Watch nowDavid Attenborough on birds of paradise – Part 2
British broadcaster Sir David Attenborough talks to Nature about his obsession with birds of paradise.
More details | Watch nowThe Mother Fish
Evidence of reproduction by internal fertilization has been discovered in a large group of ancient jawed fish. Embryos discovered within fossils of these animals confirm that live birth in prehistoric times was much more widespread than previously th....
More details | Watch nowPlatypus Genome
The duck-billed platypus is a truly unique animal; a monotreme with almost no close relatives alive on earth. Scientists just had to take a look at that genome and here they discuss their findings.
More details | Watch nowWhale Evolution
The marine mammals known as cetaceans originated about 50 million years ago in south Asia, but their terrestrial ancestor is something of a mystery. Hans Thewissen and colleagues now provide the missing Eocene piece of the jigsaw.
More details | Watch nowClimate Change: Madagascar
Anjali Nayar visited a pioneering project in Madagascar that's aiming to protect one of the country's few remaining forests. It's hoped that projects like this will help curb global warming. But first, these projects must overcome the poverty and pol....
More details | Watch nowNobel Laureate Venki Ramakrishnan
Venki Ramakrishnan was awarded the 2009 Nobel Prize in Chemistry for 'studies of the structure and function of the ribosome', the cell's protein-making factory. In this interview, he talks about his surprise at winning the prize, and what it meant to....
More details | Watch nowDavid Attenborough on Darwin – Part 1
British broadcaster Sir David Attenborough presents his views on Charles Darwin, natural selection, and how the Bible has put the natural world in peril in an exclusive interview for Nature Video.
More details | Watch nowThe Wild, Wild World of the Florida Panhandle
D. Bruce Means gives a presentation of the ecological and biological diversity of the region around the Florida panhandle. Dr. Means gave particular attention to the unique climate and environment of the area. He lists the region as one of six biol....
More details | Watch nowRecent Developments in our Understanding of the Biology of the Octopus Family
Sheeva Yazdani presents on the biology of octopuses (octopi?) and recent developments in our understanding.
More details | Watch nowThe Development, Treatment and Future of Antibiotic Resistance in Bacteria.
Branden Anglin presents on the development, treatment and possible future of antibiotic resistance in bacteria.
More details | Watch nowThe Role and Species of Beetles Worldwide
Vinnie LaBarbera presents on the role and species of beetles worldwide, including some slides of his own work at the FSU Biological Sciences Department.
More details | Watch nowUsing magnetics to repair nerve damage
A novel method of guiding nerve growth after accidents and traumas. Microscopic magnetic beads can be used to give direction to nerve re-growth.
More details | Watch nowRemarkable Creatures – Epic Adventures in the Search for the Origin of Species
A lecture given as part of the Origins 09 series at Florida State University to celebrate the 150th anniversary of Darwin's 'On the Origin of Species'. Sean B. Carroll is a professor of molecular biology and genetics at the University of Wisconsin-M....
More details | Watch nowDarwin’s Four Great Books
A lecture given as part of the Origins 09 series at Florida State University to celebrate the 150th anniversary of Darwin's 'On the Origin of Species'. Now in his 80th year, Alabama-born Edward Osborne (E.O.) Wilson has long enjoyed a reputation as ....
More details | Watch nowMax Perutz Interview – 2
The concluding part of an interview with the 1962 Nobel Laureate in Chemistry.
More details | Watch nowJacques Monod
Self-Assembly: Nature’s way to do it
Biology operates at two levels: the large scale which we can see and the underlying microscopic one. The amazing way in which intermolecular forces cause protein arrays to self-assemble, enabling Nature to fabricate the large scale components of livi....
More details | Watch nowNuts and Bolts of the Mind
Susan Greenfield conducts us on an exhilarating tour of brain. A brief fascinating historical introduction is followed by a discussion on our present, admittedly limited, understanding of this amazing organ. Members of the group handle (and dissect) ....
More details | Watch nowIn the Oceans
Satellite, ship survey and computer modelling studies of the workings of the marine environment are used explore present fish supplies worldwide. The desperate need for global 'farming' strategies necessary to ensure that the Oceans can continue to p....
More details | Watch nowFlight in Birds and Aeroplanes
John Maynard Smith, one of our most eminent evolutionary biologists and scientific communicators originally trained as an engineer and spent the war years designing aircraft. He describes the way that flight developed in the animal kingdom. The fossi....
More details | Watch nowStructural and Mechanistic Studies of Ion Channels
In this interview MacKinnon, Nobel Prizewinner in Chemistry, 2003, discusses Max Perutz and then his own research. He says his course into science was quite sequacious and he really didn't start science until he was about 30 as he had a strong intere....
More details | Watch nowThe interpretation of the genetic code and its function in protein synthesis
This interview starts with Nirenberg (Nobel Prize in Medicine, 1968) giving his recollections of his school years. He remembers going down into some limestone caves in Florida at the age of 13-14. It was full of fossilized large animal bones. In fact....
More details | Watch nowAre Genetically Modified Foods Safe?
There have been many arguments for and against GM Foods, but the question still stands - are they potential saviors of mankind or a disaster waiting to happen? This award winning video covers a range of important issues, discussed by scientists with ....
More details | Watch nowForever Young – How long can we live?
How long can we live, and how long do we want to live? Why do we change as we get old, and is there anything we can do to stop it? In this video the panel discuss ageing and some of the recent remarkable scientific advances that suggest ageing may no....
More details | Watch nowDefying Death
We can now expect to live longer than ever before, and if we get ill, we expect to be made better! However new threats continue to emerge.This presentation discusses tuberculosis and flu, new dangerous versions of old diseases, smoking and other life....
More details | Watch nowPredicting Personality
To what extent is our personality dictated by our genetic makeup? Groundbreaking new research in the fields of genetics and MRI Scanning are only now making it possible to tackle these questions, and the results are sometimes surprising. What makes u....
More details | Watch nowThe End of Evolution?
Have advances in modern medicine put an end to evolution in humans? If not, how is the human race evolving?
More details | Watch nowFred Sanger – Father of Molecular Biology
Fred Sanger is often considered the father of modern molecular biology, and is one of the few people to have been awarded two Nobel prizes. Working in Cambridge he developed a new chromatographic method for determining amino-acid end-groups. His n....
More details | Watch nowJohn Cornforth
Video of John 'Kappa' Cornforth who was born in Australia, and has been profoundly deaf since his teens. He moved into the field of organic chemistry at Sydney University where he met his wife Rita. Together they moved to Oxford and had a profound in....
More details | Watch nowGünter Blobel
Günter Blobel was awarded the Nobel Prize in Medicine/ Physiology 1999 'for the discovery that proteins have intrinsic signals that govern their transport and localization in the cell'. In this interview Blobel talks about the work that he did for t....
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