A molecular window into speech and language
Our capacity for complex speech and language remains one of the most intriguing aspects of being human. It has long been suspected that some answers to this enigma will be found buried within the genome. With recent advances in genetic technologies, ....
More details | Watch nowAdventures in vascular biology
Thirty years ago it was thought that the endothelium, a layer of thin, flat cells that line the interior surface of blood vessels was inert. However, major discoveries since then have demonstrated that it is a highly metabolic organ involved in maint....
More details | Watch nowBacterial cell walls, antibiotics and the origins of life
The cell wall is a crucial structure found in almost all bacteria. It is the target for our best antibiotics and fragments of the wall trigger powerful innate immune responses against infection. Surprisingly, many bacteria can switch almost effortl....
More details | Watch nowBeyond the human genome project
Dr Lander and his colleagues have developed many of the key tools and generated many of the key information resources for modern mammalian genomics. Their work includes mapping and sequencing of the human, mouse, and other genomes. He was elected a m....
More details | Watch nowBrain development and brain repair.
The human brain is made up of close to a trillion nerve cells (or neurons), each of which makes connections with, on average, hundreds of other nerve cells, to form the complex neuronal circuits that control all brain activities, including perception....
More details | Watch nowCloning, stem cells and regenerative medicine
Extraordinary opportunities to study the molecular mechanisms that cause inherited diseases are being provided by new methods of producing stem cells. Hear about not only the potential value of these new methods, but also how their development was pr....
More details | Watch nowCuckoos and their victims
The sight of a little warbler feeding an enormous cuckoo chick has astonished observers since ancient times. It was once thought that cuckoos were unable to raise their own young because of defective anatomy and behaviour, and so other birds were onl....
More details | Watch nowDeciphering disease: cells and disruption of their communication
The human body may seem to be no more than a bundle of tissues and organs, yet the cells these are made from are capable of interacting, communicating and performing complex tasks. Our cells' capacity to interact in this way enables humans to adapt t....
More details | Watch nowDecoding consciousness
Everything we know about the world comes to us through our brain. Yet for each of us our own conscious mental world of thoughts and feelings is isolated and private. Despite centuries of research, language or gesture remains the only way we can disco....
More details | Watch nowDeep sea discoveries
Recent underwater images show that the deep sea realm of the British Isles is nothing like the monotonous expanse of mud that many people imagine. Spectacular coral reefs, once thought to be restricted to the tropics, are now known to occur in the ch....
More details | Watch nowEngineered zinc finger proteins and gene expression
It has long been the goal of molecular biologists to design DNA binding proteins for the specific control of gene expression. The zinc finger design, discovered by Sir Aaron Klug 20 years ago, is ideally suited for such purposes, discriminating betwe....
More details | Watch nowFinding patterns in genes and proteins: decoding the logic of molecular interactions
Dr Sarah Teichmann is based at the MRC Laboratory of Molecular Biology at the University of Cambridge. In the post-genomic era, high-throughput methods are providing us with a deluge of data about genes and proteins. What knowledge about biology do....
More details | Watch nowFrom bears’ winter-sleep to advanced antibiotics
Professor Ada Yonath, Weizmann Institute of Science, Israel. To facilitate instant recovery of active life once bears wake up from their winter sleep, nature provides ingenious mechanism based on periodic packing of their ribosomes, the cellular ma....
More details | Watch nowFrom bench to bedside: KATP channels and neonatal diabetes
Whether you eat a whole box of chocolates or fast for the day, the pancreatic beta-cells ensure that your blood glucose level remains relatively constant by regulating the release of insulin from the pancreatic beta-cells. Diabetes results when insul....
More details | Watch nowFrom proteins to drugs
The normal proteins which circulate in human blood are either known or presumed to have beneficial functions. However normal immunity and inflammation proteins can cause or exacerbate disease in addition to helping to resist infections.
More details | Watch nowGenes, worms and the new genetics
A surprising finding over the past 20 years is that all animals have many of the same genes and that they use them in similar ways to grow and develop. These similarities mean that much of what is learned about what genes do in simple animals such as....
More details | Watch nowGenetic control and the mammalian radiation
To grow tissues in our body two key types of DNA control how, where and when to build essential proteins. Recent comparisons of mammal genomes show that instructions coding how to build proteins are similar across diverse species. In contrast the gen....
More details | Watch nowGenetic fingerprinting and beyond
Professor Jeffreys will describe how DNA typing can be used to solve casework and will review the latest developments, including the creation of major national DNA databases that are proving extraordinarily effective in the fight against crime.
More details | Watch nowGenetics, epigenetics and disease
The human genome sequence has been available for more than a decade, but its significance is still not fully understood. While most human genes have been identified, there is much to learn about the DNA signals that control them. This lecture describ....
More details | Watch nowHow embryos build organs to last a lifetime
All the organs of our body originate from small founder populations of cells which multiply into complex structures. ÊAdult stem cells are used to maintain organs throughout adult life and to repair or regenerate them after damage.Ê Focusing on the....
More details | Watch nowIs biodiversity going the way of the Dodo?
Panel discussion with Professor Jonathan Baillie, Dr William Cheung, Professor Adrian Lister and chaired by Dr Susan Lieberman, as part of the Royal Society Summer Science Exhibition 2011. Right now one-fifth of the world’s vertebrates are classi....
More details | Watch nowIs the Great Barrier Reef on Death Row?
Professor J.E.N Veron, the former Chief Scientist of the Australian Institute of Marine Science and widely regarded as the world's leading authority on coral reef ecosystems, presents the effects that climate change is having on coral reefs.
More details | Watch nowMagnetic brain stimulation and brain function?
Like his nineteenth century contemporaries David Ferrier tried to reveal cerebral localisation of function by direct electrical stimulation of the exposed brain of animals. With some notable exceptions the results were disappointing and confined to t....
More details | Watch nowMammalian biodiversity: past, present, future?
Beautiful and charismatic, mammals are biodiversity icons. But a quarter of mammalian species are now threatened with extinction, as ecosystems reel under the impact of a growing and ever more demanding human population. This lecture explores the his....
More details | Watch nowMapping memory: the brains behind remembering
Historically memory research has focussed on the hippocampus, a structure deep in the brain's temporal lobes. Damage to the hippocampus is known to have a devastating impact on the ability to form new memories as well as compromising recollection of ....
More details | Watch nowMicroscopy goes cold: secrets of frozen viruses
Viruses are a major cause of death and disease. Too small to be seen by light microscopy, they were first visualised about 50 years ago by electron microscopy. Dr. Crowther describes his work on the development of the methods and illustrates how he h....
More details | Watch nowMolecular chaperones: how cells stop proteins from misbehaving
Proteins are the action molecules of all cells, and to function properly, protein chains must fold and assemble correctly. But each chain of every protein runs the risk that it will combine with one or more identical chains to form nonfunctional aggr....
More details | Watch nowNature’s glass: half-full or half-empty?
Andrew Balmford FRS is Professor of Conservation Science at University of Cambridge. The world’s governments failed to meet their pledge of reducing the rate of biodiversity loss by 2010. Wild populations, their habitats, and the benefits they pr....
More details | Watch nowNetworks in ecosystems and financial systems
This talk surveys our growing understanding of the relationships between the network structure of ecological networks ? both in mathematical models and in the real world ? and their ability to withstand disturbance, natural or human-created.
More details | Watch nowNeuroNavigation: how the brain represents the space we live in and finds our way around
Learning about new environments or locating ourselves in familiar environments are some of the most fundamental tasks that the brain performs. Information is not stored in response to biological needs such as hunger or thirst but on the basis of cogn....
More details | Watch nowNobel Lives
An audience with Nobel prize winners John Sulston FRS and Sydney Brenner FRS, who talk to Sarah Montague of BBC Radio 4's Today Programme, about their lives in science and their visions for the future.
More details | Watch nowOur genomes, our history
Genetic differences between humans reflect the fundamental processes, such as mutation, recombination and natural selection, which have influenced our evolutionary history. Now that we can chart the genomes of many individuals, we are finding many su....
More details | Watch nowPandemic Influenza: one flu over the cuckoo’s nest
Where do the pandemic influenza viruses come from and why did experts fail to predict the severity of the 2009 pandemic? However to date, the 2009 H1N1 pandemic influenza has been much less severe than the 1918 Spanish influenza.
More details | Watch nowPerception, deception and reality
Sir David Attenborough delivers the 2003 Michael Faraday Lecture entitled: Perception, deception and reality
More details | Watch nowPhysical perspective on cytoplasmic streaming
Professor Ray Goldstein FRS is the Schlumberger Professor of Complex Physical Systems at the University of Cambridge. Here he describes a biological example of topological inversion, with relevance to engineering problems in human technology.
More details | Watch nowPlant and animal communication
Organisms of all kinds use signals comprising minute amounts of natural chemicals. The exploitation of semiochemicals is demonstrated with dramatic success in the management of pests and parasitic weeds in resource-poor East African cereal farming.
More details | Watch nowPlasticity of the brain: the key to human development.
How do our genes program the complexity of our brains? Why is human culture so much richer than that of the Great Apes? And how has human cognitive achievement continued to accelerate, when our genetic makeup has changed very little over the past 100....
More details | Watch nowRegenerating organs and other small challenges
A disagreeable side effect of longer life-spans is the failure of one part of the body – the knees, for example – before the body as a whole is ready to surrender. The search for replacement body parts has fueled the highly interdisciplinary fiel....
More details | Watch nowReprogramming the code of life
The information for synthesizing the molecules that allow organisms to survive and replicate is encoded in genomic DNA. In the cell, DNA is copied to messenger RNA, and triplet codons in the messenger RNA are decoded in the process of translation to ....
More details | Watch nowScience not stamp collecting? Botany from 1759 to 2059
Professor Hopper considers the vital role that the study of plant taxonomy and systematics has played in plant science. He considers, in particular, how these fields are transforming to meet the needs of 21st Century science as we address the challen....
More details | Watch nowStem Cells to Synapses
One of the goals of research in neurobiology is the repair and regeneration of neurons after damage to the brain or spinal cord. Before we can understand how to repair the nervous system we must first learn how the nervous system is put together.
More details | Watch nowStructure and the living cell
In this lecture Iain Campbell will discuss methods of studying the structure of molecules and cells and how they have advanced in the 350 years since early microscopes gave the first glimpse of single cells. He will show how modern methods are allowi....
More details | Watch nowTargeting the human kinome: cancer drug discovery
This lecture discusses how the discovery of the Philadelphia chromosome provided the first example of a link between cancer and a recurrent genetic abnormality. This chromosomal translocation, which results in activation of the Abl protein kinase, re....
More details | Watch nowThe great ideas of biology
Three of the ideas of biology are the gene theory, the theory of evolution by natural selection and the proposal that the cell is the fundamental unit of all life. A fourth idea is that the organization of chemistry within the cell provides explanati....
More details | Watch nowThe new biology of ageing
Research into ageing has been rejuvenated by the discovery of mutations in single genes that extend the lifespan of laboratory animals. Some of the signalling pathways involved, particularly the insulin/Igf-like pathway, have effects on lifespan acro....
More details | Watch nowThe origins of flowers
Flowers are such a ubiquitous and familiar part of our modern world that it is easy to take them for granted. But as Darwin recognized, the exquisite details of their structure and appearance have been shaped by evolutionary processes over millions o....
More details | Watch nowThe Puppet Master: How the brain controls the body
The effortless ease with which humans move our arms, our eyes, even our lips when we speak masks the true complexity of the control processes involved. Professor Daniel Wolpert explains how the brain deals with this and can perform optimally in the p....
More details | Watch nowThe Zoological World of Edward Lear
Clemency Fisher is Curator of Vertebrate Zoology at National Museums Liverpool. Edward Lear is most famous for his Nonsense Rhymes, such as “The Owl and the Pussycat” and “The Quangle Wangle’s Hat”, but he was also a talented zoological art....
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