From the Structure of the Ribosome to New Antibiotics
Structural studies of the ribosome exemplify the evolution of structural studies in cell biology from the early negatively stained images of macromolecular assemblies in whole cells, to a detailed atomic understanding of the mechanisms of action of a....
More details | Watch nowThe Amazing Ribosome
Ribosomes are the universal cellular machines that act as polymerases that translate the genetic code into proteins. They posses spectacular architecture accompanied by inherent mobility that facilitate their smooth performance in decoding, peptide ....
More details | Watch nowMolecular Machines for Protein Degradation Inside Cells
Within cells or subcellular compartments misfolded and/or short-lived regulatory proteins are degraded by protease machines, cage-forming multi-subunit assemblages. Their proteolytic active sites are sequestered within the particles and located on t....
More details | Watch nowProteasome and DegP Protease, Mechanisms and Drug Design
Within cells or subcellular compartments, mis-folded and/or short-lived regulatory proteins are degraded by protease machines, cage-forming multi-subunit assemblages, the proteasome and HtrA/DegP. They are essential components in very complex regul....
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Philip Shlenoff, recent high school graduate, gives a presentation of his work and opportunity at the Florida State University Dept. of Chemistry. Under the supervision of Zaki Estephan, Philip has actively participated in research that targets canc....
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