12 results found for cancer

The selective degradation of many short-lived proteins in eukaryotic cells is carried out by the ubiquitin-mediated proteolytic system. In this pathway, proteins are targeted for degradation by covalent ligation to ubiquitin, a highly conserved small....

The role of nitric oxide in cellular signaling in the past three decades has become one of the most rapidly growing areas in biology. Nitric oxide is a gas and a free radical with an unshared electron that can regulate an ever-growing list of biolog....

For cancer diagnosis and therapy, we are developing activatable cell-penetrating peptides (ACPPs), synthetic molecules with a novel amplifying mechanism for homing to diseased tissues. ACPPs are polycationic cell-penetrating peptides whose cellular ....

Biological research and medicine were transformed by the invention and improvement of the optical microscope. Since the early 1990s, there has been another revolution in optical imaging, and manipulation of individual biological molecules and bio-mo....

Slightly more than 20% of the global cancer incidence is presently being linked to viral, bacterial, or parasitic infections. The mechanisms by which these agents mediate malignant transformation differ substantially. Some contribute directly, freq....

It is now axiomatic that, no matter what its causes, cancer ultimately arises from the malfunction of genes. A number of clues prefigured this paradigm: the persistence of the malignant phenotype through countless cell divisions; the mutagenicity of....

The epidemiology of Helicobacter pylori continues to be an area of discovery and controversy in the 21st century. The transmission of this bacterium from mother to child allows Helicobacter DNA to mimic the evolution of maternal mitochondria DNA. B....

The selective degradation of many short-lived proteins in eukaryotic cells is carried out by the ubiquitin-mediated proteolytic system.  In this pathway, proteins are targeted for degradation by covalent ligation to ubiquitin, a highly conserved sma....

The selective degradation of many short-lived proteins in eukaryotic cells is carried out by the ubiquitin-mediated proteolytic system.  In this pathway, proteins are targeted for degradation by covalent ligation to ubiquitin, a highly conserved sma....

The lecture will be devoted to the topic of how the biological world supplies itself with energy to make biology work, and what medical consequences ensue when the energy supply chain in our bodies is damaged or defective.  We derive our energy from....

The selective degradation of many short-lived proteins in eukaryotic cells is carried out by the ubiquitin-mediated proteolytic system.  In this pathway, proteins are targeted for degradation by covalent ligation to ubiquitin, a highly conserved sma....

Philip Shlenoff, recent high school graduate, gives a presentation of his work and opportunity at the Florida State University Dept. of Chemistry. Under the supervision of Zaki Estephan, Philip has actively participated in research that targets canc....