Advances in Olefin Metathesis Employing Molybdenum and Tungsten Catalysts
Olefin metathesis is an irresistible way to make C=C bonds catalytically in organic molecules and polymers, both as a consequence of its very nature, i.e. the synthesis of C=C bonds from C=C bonds, and because of the control that can be exercised thr....
More details | Watch nowCatalysis at Surfaces: From Atoms to Complexity
Catalysis by solid surfaces is, among others, of importance for the chemical industry (e.g. the Haber-Bosch process) as well as for environmental chemistry (car exhaust catalyst). Surface physical techniques enable investigation of the underlying e....
More details | Watch nowChemistry: the Key to Our Future
Chemistry is not merely a science of making observations in order to better understand Nature. Our science is creative and productive, generating substances of very high value from almost nothing. Chemists already have made enormous contribution to....
More details | Watch nowCross-Coupling Reactions of Organoboranes: An Easy Way for Carbon-Carbon Bonding
The palladium-catalyzed cross-coupling reaction between different types of organoboron compounds and various organic halides in the presence of base provides a powerful and general methodology for the formation of carbon-carbon bonds. The (sp3)C-B ....
More details | Watch nowDarwinian evolution as understood by scientists of the 21st century
After a short reminder of the historical development of evolutionary biology, elements to a molecular theory of Darwinian evolution will be presented. Biological evolution is driven by the availability of genetic variants in populations. The occasi....
More details | Watch nowFrom Atoms to Complexity: Reactions at Surfaces
The interaction of molecules with the surfaces of solids forms the basis of heterogeneous catalysis and can now be investigated in atomic detail. Systems of this kind may, on the other hand, serve as models for studying self-organisation of matter le....
More details | Watch nowMolecular Catalysis for Green Chemistry
Science is inevitably intertwined with society. The state of the art of science, coupled with industrial endeavors, has determined our quality of life. Chemists are proud of their ability to generate high value from almost nothing by using accumu....
More details | Watch nowNitric oxide as a messenger molecule and its role in drug development
The role of nitric oxide in cellular signaling in the past three decades has become one of the most rapidly growing areas in biology. Nitric oxide is a gas and a free radical with an unshared electron that can regulate an ever-growing list of biolog....
More details | Watch nowProtein Crosstalk in Cell Signaling
This talk concentrates on cellular regulation by tyrosine phosphorylation which has been directly implicated in cell growth, differentiation and transformation. Growth factor receptors transduce their signal by recruiting a multiplicity of adaptor p....
More details | Watch nowRecent Advances in Olefin Metathesis Catalyzed by Molybdenum and Tungsten Alkylidene Complexes
In the process of preparing M(NR)(CHCMe2R')(OR")2 (R' = Me or Ph) species (or analogs that contain enantiomerically pure biphenolate or binaphtholate ligands) in situ by treating M(NR)(CHCMe2R')(pyrrolide)2 species with alcohols, we have discovered M....
More details | Watch nowRNAi and development in C. elegans
Argonaute proteins interact with small RNAs to mediate gene silencing. C. elegans contains 27 Argonaute homologs, raising the question of what roles these genes play in RNAi and related gene-silencing pathways. Through our collaborator, Dr. Shohei....
More details | Watch nowThe cell cycle and cancer
It was in 1882 that Walther Flemming published drawings of chromosomes lining up in mitosis and parting equally to the daughters of cell division, and 20 years later that Theodor Boveri explained the significance of the chromosome dance in terms of t....
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