43 results found for chemistry

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00:33:00

Nanoscopy – allowing molecules to be examined inside living cells

by Eric Betzig
Nanoscopy – allowing molecules to be examined inside living cells
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 2860 views
Rating:

Eric Betzig shared the 2014 Chemistry Nobel prize with fellow American William E. Moerner and Romanian-German Stefan W. Hell for revolutionising science through the development of super-resolved fluorescence to exceed the accepted limits of tradition....

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00:30:00

The Hunt May Be Up for the Carrier of the Diffuse Interstellar Bands and other stories

by Harry Kroto
The Hunt May Be Up for the Carrier of the Diffuse Interstellar Bands and other stories
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1408 views
Rating:

The development of radio telescopes has revolutionized our understanding of the molecular constitution of the interstellar medium ISM. A recent surprise that the element carbon had up its sleeve was the existence of C60, Buckminsterfullerene, the thi....

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00:32:00

Fun with Light and Single Molecules

by William Moerner
Fun with Light and Single Molecules
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1236 views
Rating:

More than 25 years ago, single molecules were first detected optically, but how do we really detect a single molecule today, and what good is it? It is an amazing fact that you can even detect single molecules with your own eyes. When a new regime of....

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00:29:00

Electron Transfer Theory in Single Molecule Studies of Intermittent Fluorescence of Quantum Dots and in Initial Steps in Dye Sensitized Solar Cells

by Rudolph Marcus
Electron Transfer Theory in Single Molecule Studies of Intermittent Fluorescence of Quantum Dots and in Initial Steps in Dye Sensitized Solar Cells
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1503 views
Rating:

Intermittently fluorescing single molecule systems are found in many materials, including semiconductor quantum dots (QD), dyes on crystalline or nanoparticle film surfaces, and biological systems. The QD's show a ~ -3/2 power law for the distributio....

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00:33:00

Molecules Against Cancer or for Long-Term Memory Storage

by Roger Tsien
Molecules Against Cancer or for Long-Term Memory Storage
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1188 views
Rating:

For cancer diagnosis and therapy, we are developing activatable cell penetrating peptides (ACPPs), synthetic molecules with a novel amplifying mechanism for homing to diseased tissues. ACPPs are polycationic cell penetrating peptides whose cellular u....

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00:26:00

NMR in Biology, Chemistry and Medicine

by Kurt Wurthrich
NMR in Biology, Chemistry and Medicine
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1649 views
Rating:

For the discovery of the physics phenomenon of nuclear magnetic resonance (NMR), Felix Bloch and Edward Purcell were awarded the Nobel Prize in Physics in 1952. NMR has then been used in a wide range of fundamental studies in physics, and in the 1960....

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00:35:00

How to Synthesize a Wide Variety of Optically Active Compounds with >99% Optical Purity

by Ei-ichi Negishi
How to Synthesize a Wide Variety of Optically Active Compounds with >99% Optical Purity
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1460 views
Rating:

The discovery and synthetic applications of a widely applicable and highly enantioselective (>99% ee) protocol consisting of the 'ZACA reaction' (Zr-catalyzed asymmetric carboalumination of alkenes), purification of the ZACA-products by lipase-cat....

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00:31:00

Catalysis at Surfaces: From Atoms to Complexity

by Gerhard Ertl
Catalysis at Surfaces: From Atoms to Complexity
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1254 views
Rating:

This lecture addresses the question if spatio-temporal self-organisation of matter which is so characteristic for living systems can also be verified with a simple inorganic reaction in which the observed phenomena of complexity can be traced back to....

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00:27:00

Roles of the Ubiquitin System in Health and Disease

by Avram Hershko
Roles of the Ubiquitin System in Health and Disease
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1299 views
Rating:

The selective degradation of many short-lived proteins in eukaryotic cells is carried out by the ubiquitin-mediated proteolytic system. In this pathway, proteins are targeted for degradation by covalent ligation to ubiquitin, a highly conserved small....

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00:31:00

Structural Aspects of Protease Control in Health and Disease

by Robert Huber
Structural Aspects of Protease Control in Health and Disease
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1297 views
Rating:

This lecture starts out with a very brief review of the history of protein crystallography and continue with our studies since 1970 on proteolytic enzymes and their control. Proteolytic enzymes catalyse a very simple chemical reaction, the hydrolytic....

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00:33:00

Towards Adaptive Chemistry

by Jean-Marie Lehn
Towards Adaptive Chemistry
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1332 views
Rating:

Molecular chemistry implementing reversible chemical bonds between atoms in molecules, as well as supramolecular chemistry, whose molecular components are held together by intermolecular interactions, are able to undergo a continuous change in consti....

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00:32:00

Aquaporin Water Channels – From Atomic Structure to Malaria

by Peter Agre
Aquaporin Water Channels – From Atomic Structure to Malaria
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 2920 views
Rating:

Aquaporin channels allow water to rapidly cross cell membranes in all living organisms. AQP1 confers red cells and proximal renal tubules with high water permeability. Present in renal collecting duct, AQP2 is regulated by vasopressin, and human muta....

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00:31:00

Seeing is Believing – A Hundred Years of Visualizing Molecules

by Venkatraman Ramakrishnan
Seeing is Believing – A Hundred Years of Visualizing Molecules
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 1205 views
Rating:

It has been a hundred years since molecules were first visualized directly by using x-ray crystallography. That gave us our first look at molecules as simple as common salt to one as complex as the ribosome that has almost a million atoms. In the las....

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00:34:00

The Dawn of the Fullerenes: A Research Adventure

by Robert Curl
The Dawn of the Fullerenes: A Research Adventure
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1605 views
Rating:

When he received the 1996 Nobel Prize in Chemistry together with Richard E. Smalley (who also worked at Rice) and Sir Harold Kroto (at the time at the University of Sussex, UK), this was a true example of national and international scientific collabo....

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00:32:00

C60-Buckminsterfullerene: Not just a Pretty Molecule

by Harry Kroto
C60-Buckminsterfullerene: Not just a Pretty Molecule
for 14-19 and upwards,
Lectures | 14-19 and upwards | 9 years ago | 1907 views
Rating:

Amongst the Nobel Laureates lecturing in Lindau, Sir Harold Kroto would probably earn the award for the most unusual and characteristic way of presenting. This lecture, which is the first he ever gave in Lindau, is no exception. Kroto`s way of presen....

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00:49:00

Dynamics of Chemical Reactions

by Yuan Lee
Dynamics of Chemical Reactions
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1260 views
Rating:

Every macroscopic chemical transformation, whether it is atmospheric ozone depletion or the burning of a candle, consists of millions of microscopic chemical events, which involve collisions between molecules.  It has been the dream of scientists fo....

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00:35:00

From Disorder to Order

by Gerhard Ertl
From Disorder to Order
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1196 views
Rating:

Our experience suggests that a system will usually show the tendency to undergo spontaneously a transition from the state of order into disorder.  Quite in contrast, our world developed from an initial state of great disorder into another one where ....

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00:39:00

Molecular Catalysis for Green Chemistry

by Ryoji Noyori
Molecular Catalysis for Green Chemistry
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1355 views
Rating:

Science is inevitably intertwined with society.  The state of the art of science, coupled with industrial endeavors, has determined our quality of life.  Chemists are proud of their ability to generate high value from almost nothing by using accumu....

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00:35:00

Designing Molecules and Nanoparticles to Help See and Treat Disease

by Roger Tsien
Designing Molecules and Nanoparticles to Help See and Treat Disease
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1232 views
Rating:

Molecules to observe and manipulate biological systems can be devised by a variety of strategies, ranging from pure chemical design and total synthesis to genome mining and high-throughput directed evolution. Examples of both successes and failures a....

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00:40:00

Why I love Microbes

by Richard Roberts
Why I love Microbes
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1529 views
Rating:

We live in a fascinating world surrounded by life. Much of that life is clearly visible like the plants and animals that we see every day. However, far more is invisible to the naked eye and it is to this realm, the microscopic world, that I will t....

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00:51:00

Why do we not have a vaccine against TB or HIV (yet)?

by Ralph Zinkernagel
Why do we not have a vaccine against TB or HIV (yet)?
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1204 views
Rating:

Survival of vertebrate hosts against infections depends on important natural or innate resistance mechanisms combined with adaptive immune responses of T and B cells. Infectious agents probe the limit of immune responses and help to characterize thr....

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00:46:00

Darwinian evolution as understood by scientists of the 21st century

by Werner Arber
Darwinian evolution as understood by scientists of the 21st century
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1801 views
Rating:

After a short reminder of the historical development of evolutionary biology, elements to a molecular theory of Darwinian evolution will be presented. Biological evolution is driven by the availability of genetic variants in populations. The occasi....

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00:38:00

Protein Crosstalk in Cell Signaling

by Edmond Fischer
Protein Crosstalk in Cell Signaling
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1402 views
Rating:

This talk concentrates on cellular regulation by tyrosine phosphorylation which has been directly implicated in cell growth, differentiation and transformation. Growth factor receptors transduce their signal by recruiting a multiplicity of adaptor p....

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00:12:00

The cell cycle and cancer

by Tim Hunt
The cell cycle and cancer
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 2102 views
Rating:

It was in 1882 that Walther Flemming published drawings of chromosomes lining up in mitosis and parting equally to the daughters of cell division, and 20 years later that Theodor Boveri explained the significance of the chromosome dance in terms of t....

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01:05:00

RNAi and development in C. elegans

by Craig Mello
RNAi and development in C. elegans
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 2169 views
Rating:

Argonaute proteins interact with small RNAs to mediate gene silencing. C. elegans contains 27 Argonaute homologs, raising the question of what roles these genes play in RNAi and related gene-silencing pathways. Through our collaborator, Dr. Shohei....

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00:51:00

Nitric oxide as a messenger molecule and its role in drug development

by Ferid Murad
Nitric oxide as a messenger molecule and its role in drug development
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1377 views
Rating:

The role of nitric oxide in cellular signaling in the past three decades has become one of the most rapidly growing areas in biology. Nitric oxide is a gas and a free radical with an unshared electron that can regulate an ever-growing list of biolog....

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00:39:00

Recent Advances in Olefin Metathesis Catalyzed by Molybdenum and Tungsten Alkylidene Complexes

by Richard Schrock
Recent Advances in Olefin Metathesis Catalyzed by Molybdenum and Tungsten Alkylidene Complexes
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1621 views
Rating:

In the process of preparing M(NR)(CHCMe2R')(OR")2 (R' = Me or Ph) species (or analogs that contain enantiomerically pure biphenolate or binaphtholate ligands) in situ by treating M(NR)(CHCMe2R')(pyrrolide)2 species with alcohols, we have discovered M....

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00:35:00

From ‘On Water’ and Enzyme Catalysis to Single Molecules and Quantum Dots, Theory and Experiment

by Rudolph Marcus
From ‘On Water’ and Enzyme Catalysis to Single Molecules and Quantum Dots, Theory and Experiment
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1537 views
Rating:

Much of theoretical chemistry has involved equations and their application to experiments, Debye, Debye-Hueckel, Transition State Theory, Kramers, LCAO, RRKM, among others. In fortunate circumstances one can, as in a theory of electron transfer reac....

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00:31:00

Chemistry: the Key to Our Future

by Ryoji Noyori
Chemistry: the Key to Our Future
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1386 views
Rating:

Chemistry is not merely a science of making observations in order to better understand Nature. Our science is creative and productive, generating substances of very high value from almost nothing. Chemists already have made enormous contribution to....

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00:34:00

Greenhouse Gases and Climate Change

by Sherwood Rowland
Greenhouse Gases and Climate Change
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1580 views
Rating:

The 'greenhouse gases (GHG)' intercept a fraction of outgoing terrestrial infrared radiation, creating the natural greenhouse effect which warmed the atmosphere by approximately 32 Celsius at the beginning of the 20th Century. The activities of manki....

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00:31:00

From Atoms to Complexity: Reactions at Surfaces

by Gerhard Ertl
From Atoms to Complexity: Reactions at Surfaces
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1337 views
Rating:

The interaction of molecules with the surfaces of solids forms the basis of heterogeneous catalysis and can now be investigated in atomic detail. Systems of this kind may, on the other hand, serve as models for studying self-organisation of matter le....

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00:23:00

Atmospheric Chemistry and Climate in the Anthropocene

by Paul Krutzen
Atmospheric Chemistry and Climate in the Anthropocene
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1253 views
Rating:

Despite their relatively small mass, 10% of the earth biosphere as a whole, generations of ambitious ‘homo sapiens’ have already played a major and increasing role in changing basic properties of the atmosphere and the earth’s surface.  Human ....

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00:30:00

Photosynthesis, Biomass, Biofuels: Conversion Efficiencies and Consequences

by Hartmut Michel
Photosynthesis, Biomass, Biofuels: Conversion Efficiencies and Consequences
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1304 views
Rating:

It is generally accepted that the global warming, which we undoubtedly observe, is the result of an increased concentration of greenhouse gases like carbon dioxide and methane in the atmosphere.  Within this scenario it is evident that we have to re....

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00:36:00

Magical Power of d-Block Transition Metals: Past, Present and Future

by Ei-ichi Negishi
Magical Power of d-Block Transition Metals: Past, Present and Future
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1254 views
Rating:

Until recently, most of the 24 d-block transition metals had been used primarily as useful materials for (i) construction and also as tools and containers, etc., (Ti, Zr, Fe and their alloys with V, Cr, Mn, Co, Ni, etc.), (ii) precious and ornamental....

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00:40:00

Glimpses of Chemical Wizardry

by Dudley Herschbach
Glimpses of Chemical Wizardry
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 968 views
Rating:

In an evangelical spirit, three vignettes will be presented that have the character of molecular parables: stories with lessons that transcend the specific details.(1) How knowledge of the orientation of a methyl group with respect to a neighboring d....

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00:30:00

Catalysis at Surfaces: From Atoms to Complexity

by Gerhard Ertl
Catalysis at Surfaces: From Atoms to Complexity
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1436 views
Rating:

Catalysis by solid surfaces is, among others, of importance for the chemical industry (e.g. the Haber-Bosch process) as well as for environmental chemistry (car exhaust catalyst).  Surface physical techniques enable investigation of the underlying e....

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00:30:00

Cross-Coupling Reactions of Organoboranes: An Easy Way for Carbon-Carbon Bonding

by Akira Suzuki
Cross-Coupling Reactions of Organoboranes: An Easy Way for Carbon-Carbon Bonding
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 2472 views
Rating:

The palladium-catalyzed cross-coupling reaction between different types of organoboron compounds and various organic halides in the presence of base provides a powerful and general methodology for the formation of carbon-carbon bonds.  The (sp3)C-B ....

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00:27:00

G Protein Coupled Receptors: Challenges for Drug Discovery

by Brian Kobilka
G Protein Coupled Receptors: Challenges for Drug Discovery
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1433 views
Rating:

G protein coupled receptors (GPCRs) conduct the majority of cellular responses to hormones and neurotransmitters, and are therefore the largest group of pharmaceutical targets for a broad spectrum of diseases.  Identification of genes for GPCRs, ini....

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00:34:00

Advances in Olefin Metathesis Employing Molybdenum and Tungsten Catalysts

by Richard Schrock
Advances in Olefin Metathesis Employing Molybdenum and Tungsten Catalysts
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1632 views
Rating:

Olefin metathesis is an irresistible way to make C=C bonds catalytically in organic molecules and polymers, both as a consequence of its very nature, i.e. the synthesis of C=C bonds from C=C bonds, and because of the control that can be exercised thr....

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00:31:00

Green Chemistry and Catalysis

by Robert Grubbs
Green Chemistry and Catalysis
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1196 views
Rating:

Much of the chemical industry is based on processes that were developed decades ago.  The change in the cost of petroleum carbon and energy sources and the need to control emissions of carbon dioxide and other pollutants will change the rules of the....

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00:35:00

Perspectives in Chemistry – Towards Adaptive Chemistry

by Jean-Marie Lehn
Perspectives in Chemistry – Towards Adaptive Chemistry
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1457 views
Rating:

Supramolecular chemistry lies beyond molecular chemistry.  It aims at implementing highly complex chemical systems from molecular components held together by non-covalent intermolecular forces and effecting molecular recognition, catalysis and trans....

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00:32:00

Single Molecule Studies of Initial Steps in Dye Sensitized Solar Cells and of Quantum Dots – Examples of Electron Transfers and Relation to Ensemble Studies

by Rudolph Marcus
Single Molecule Studies of Initial Steps in Dye Sensitized Solar Cells and of Quantum Dots – Examples of Electron Transfers and Relation to Ensemble Studies
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1606 views
Rating:

We consider two fields of single molecule studies of intermittently fluorescing systems.  In both fields the intermittency is assumed to involve diffusion controlled electron transfer.  One of these studies involves the initial steps in dye-sensiti....

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00:38:00

Widen Your Scope by Extracurricular Activities: My Example

by Richard Ernst
Widen Your Scope by Extracurricular Activities: My Example
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1164 views
Rating:

Some observers might think that fierce scientific competition borders on a rat race.  According to Wikipedia: "A rat race is an endless, self-defeating, or pointless pursuit.  It conjures up the image of the futile efforts of a lab rat trying to es....

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