Polyelectrolyte Multilayers Controlling Protein Adsorption etc.

View Polyelectrolyte Multilayers Controlling Protein Adsorption etc. Moussallem

Presenter: Maroun D Moussallem

Published: March 2008

Age: 22 and upwards

Views: 810 views

Tags: grad

Type: Lectures

Source/institution: FSU

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A7r5 smooth muscle cells cultured on different polyelectrolyte multilayer (PEMU) thin films behaved differently. Cells Adhered and spread well on nafion terminated PEMUs, they attached less and migrated more on poly(allylamine hydrochloride) (PAH) terminated films and they were repelled by all surfaces terminated with a copolymer of acrylic acid and 3-[2-(acrylamido)-Et dimethylammonio] propane sulfonate (PAA-co-PAEDAPS). Fibronectin bound best to PAH and nafion terminated PEMUs but bound poorly to PEMUs terminated with PAA-co-PAEDAPS. Both cells and FN attached onto nafion much better than PAA-co-PAEDAPS on a micropatterned surface.