Engineered zinc finger proteins and gene expression
Presenter: Aaron Klug
Published: January 2010
Age: 18-22 and upwards
Views: 1223 views
Source/institution: Royal Society
It has long been the goal of molecular biologists to design DNA binding proteins for the specific control of gene expression. The zinc finger design, discovered by Sir Aaron Klug 20 years ago, is ideally suited for such purposes, discriminating between closely related sequences both in vitro and in vivo.