45 results found for proteins

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Adventures in Nontranslational Research - Lindau-Nobel - Martin Chalfie - Chemistry 2010 00:27:00

Adventures in Nontranslational Research

by Martin Chalfie
Adventures in Nontranslational Research
for 18-22 and upwards,
Lectures | 18-22 and upwards | 5 years ago | 835 views
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Professor Martin Chalfie regrets the disproportionately high funding of translational research, defined as applied research for the treatment of human diseases.  With examples from the research in his lab he wants to show how important nontranslatio....

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Aquaporin - L-N - Agre - Medicine 2014 00:32:00

Aquaporin Water Channels _ From Atomic Structure to Malaria

by Peter Agre
Aquaporin Water Channels _ From Atomic Structure to Malaria
for 18-22 and upwards,
Lectures | 18-22 and upwards | 5 years ago | 2317 views
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Aquaporin (AQP) water channel proteins enable high water permeability in certain biological membranes. Discovered in human red cells but expressed in multiple tissues, AQP1 has been thoroughly characterized and its atomic structure is known. Expres....

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Aquaporin Water Channels - From Atomic Structure to Malaria Lindau-Nobel Peter Agre 2013 00:30:00

Aquaporin Water Channels: From Atomic Structure to Malaria

by Peter Agre
Aquaporin Water Channels: From Atomic Structure to Malaria
for 18-22 and upwards,
Lectures | 18-22 and upwards | 5 years ago | 1641 views
Rating:

Aquaporin (AQP) water channel proteins enable high water permeability of certain biological membranes.  Discovered in human red cells but expressed in multiple tissues, AQP1 has been thoroughly characterized and its atomic structure is known.  Expr....

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Basic Science and Co-entrepreneurship, my Experience -Lindau-Nobel - Robert Huber - Chemistry 2010 00:45:00

Basic Science and Co-entrepreneurship, my Experience

by Robert Huber
Basic Science and Co-entrepreneurship, my Experience
for 18-22 and upwards,
Lectures | 18-22 and upwards | 5 years ago | 623 views
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The design and development of inhibiting (or occasionally activating) ligands of target proteins in medicine and crop protection guided by molecular structures and functions has become an established technology in academia and industry recently._ Dr....

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Bioinspired genotype 00:32:00

Bioinspired genotype–phenotype linkages

by Florian Hollfelder
Bioinspired genotype–phenotype linkages
for 14-19 and upwards,
Lectures | 14-19 and upwards | 4 years ago | 711 views
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Florian Hollfelder is based in the Department of Biochemistry at the University of Cambridge. He is interested in mechanism in chemistry and biology. Here he describes using principles of natural selection to make functional proteins.

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Ciechanover 00:06:00

Breaking down Altzheimer’s

by Aaron Ciechanover
Breaking down Altzheimer’s
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1243 views
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Alzheimer's disease is caused by abnormal clumps or aggregations of proteins in the brain. Simon P”psel is about to embark on PhD work on a protein that might help us to treat this devastating disease, and Nobel Prize winning biochemist Aaron Ciech....

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Medina 00:09:00

Breast Cancer Susceptibility Gene BRCA2

by Angelica Medina
Breast Cancer Susceptibility Gene BRCA2
for 18-22 and upwards,
Lectures | 18-22 and upwards | 8 years ago | 882 views
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BRAC2 is a tumor suppressor gene. Its protein product interacts with other proteins to assist regulation of DNA repair, transcription and cell cycle checkpoints. BRAC2 gene disruption may lead to protein truncation, mutations and loss of function. Ce....

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Building - L-N - Tsien - Chem 2009 00:41:00

Building and Breeding Molecules to Spy on Cells, Tumors, and Organisms

by Roger Tsien
Building and Breeding Molecules to Spy on Cells, Tumors, and Organisms
for 18-22 and upwards,
Lectures | 18-22 and upwards | 5 years ago | 793 views
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Molecules to observe and manipulate biological systems can be devised by a variety of strategies, ranging from pure chemical design and total synthesis to genome mining and high-throughput directed evolution. Examples of both successes and failures ....

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10 Climbing the Everest Beyond the Everest - Lindau-Nobel - Ada Yonath - Medicine 2011 00:41:00

Climbing the Everest Beyond the Everest

by Ada Yonath
Climbing the Everest Beyond the Everest
for 18-22 and upwards,
Lectures | 18-22 and upwards | 5 years ago | 1119 views
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The challenges associated with pursuing ribosomal crystallography can be described as a series of Everest climbing. At each step, when reaching the summit, a taller and more difficult one became exposed. Snapshots of this story will be described.__....

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Conformational Plasticity of G-Protein-Coupled Receptors (GPCRs) studied by NMR in Solution Lindau-Nobel Kurt Wuthrich 2013 00:38:00

Conformational Plasticity of G-Protein-Coupled Receptors (GPCRs) studied by NMR in Solution

by Kurt Wurthrich
Conformational Plasticity of G-Protein-Coupled Receptors (GPCRs) studied by NMR in Solution
for 18-22 and upwards,
Lectures | 18-22 and upwards | 5 years ago | 923 views
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As an introduction, some principles of nuclear spin physics applying to studies of integral membrane proteins (IMP) will be reviewed.  Applications of resulting nuclear magnetic resonance (NMR) techniques will then be illustrated with studies of G-p....

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Curiosity and its Fruits: From Basic Science to Advanced Medicine Lindau-Nobel Ada Yonath 2013 00:33:00

Curiosity and its Fruits: From Basic Science to Advanced Medicine

by Ada Yonath
Curiosity and its Fruits: From Basic Science to Advanced Medicine
for 18-22 and upwards,
Lectures | 18-22 and upwards | 5 years ago | 714 views
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Ribosomes, the universal cellular machines that translate the genetic code into proteins, are targeted by many antibiotics that paralyze them by binding to their functional sites.  Antibiotics binding modes, inhibitory actions and synergism pathways....

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Klug 01:08:00

Engineered zinc finger proteins and gene expression

by Aaron Klug
Engineered zinc finger proteins and gene expression
for 18-22 and upwards,
Lectures | 18-22 and upwards | 9 years ago | 1190 views
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It has long been the goal of molecular biologists to design DNA binding proteins for the specific control of gene expression. The zinc finger design, discovered by Sir Aaron Klug 20 years ago, is ideally suited for such purposes, discriminating betwe....

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