12 results found for antibiotics

The cell wall is a crucial structure found in almost all bacteria. It is the target for our best antibiotics and fragments of the wall trigger powerful innate immune responses against infection. Surprisingly, many bacteria can switch almost effortl....

Aditya and William give a cartoonists vision of this important subject.

Structural studies of the ribosome exemplify the evolution of structural studies in cell biology from the early negatively stained images of macromolecular assemblies in whole cells, to a detailed atomic understanding of the mechanism of action of a ....

The challenges associated with pursuing ribosomal crystallography can be described as a series of Everest climbing. At each step, when reaching the summit, a taller and more difficult one became exposed. Snapshots of this story will be described.__....

Structural studies of the ribosome exemplify the evolution of structural studies in cell biology from the early negatively stained images of macromolecular assemblies in whole cells, to a detailed atomic understanding of the mechanisms of action of a....

Ribosomes are the universal cellular machines that act as polymerases that translate the genetic code into proteins. They posses spectacular architecture accompanied by inherent mobility that facilitate their smooth performance in decoding, peptide ....

Within cells or subcellular compartments, mis-folded and/or short-lived regulatory proteins are degraded by protease machines, cage-forming multi-subunit assemblages, the proteasome and HtrA/DegP.  They are essential components in very complex regul....

Ribosomes, the universal cellular machines that translate the genetic code into proteins, are targeted by many antibiotics that paralyze them by binding to their functional sites.  Antibiotics binding modes, inhibitory actions and synergism pathways....

Professor Ada Yonath, Weizmann Institute of Science, Israel.  To facilitate instant recovery of active life once bears wake up from their winter sleep, nature provides ingenious mechanism based on periodic packing of their ribosomes, the cellular ma....

Contagions, or infectious diseases, which kill both fascinate and frighten us. Far from receding in importance as was expected fifty years ago in the heyday of new antibiotic discovery, infectious diseases remain a major cause of suffering and death ....

Lucas Paladino gives a brief overview of the development, use and impact of penicillin.

Branden Anglin presents on the development, treatment and possible future of antibiotic resistance in bacteria.